ceroplastol II

Base Information

• Chemical Name: ceroplastol II
• CAS No.: 119903-98-9
• Molecular Formula: C₂₅H₄₀O
• Molecular Weight: 356.592
• Mol file: 119903-98-9.mol

Synonyms:

Chemical Property of ceroplastol II

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ceroplastol II

There total 22 articles about ceroplastol II which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

ceroplastol II 3,5-dinitrobenzoate (122347-07-3) → ceroplastol II (23518-96-9,119903-98-9)

Guidance literature:

With sodium hydroxide; In methanol; for 1h; Heating;

Reference yield: 75.0%

ethyl albolate (120354-85-0,122356-56-3) → ceroplastol II (23518-96-9,119903-98-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

Reference yield:

(R)-2-{(1R,2R,3S)-3-[(S)-5-((R)-2-Benzyloxy-1-methyl-ethyl)-2-methyl-cyclopent-1-enylmethyl]-2-hydroxymethyl-3-methyl-cyclopentyl}-propan-1-ol (120410-13-1) → ceroplastol II (23518-96-9,119903-98-9)

Guidance literature:

Multi-step reaction with 18 steps

1: 89 percent / pyridine

2: 95 percent / pyridine

3: H₂ / Pd/C

4: (COCl)2, DMSO, Et₃N / CH₂Cl₂

5: 98 percent / Et₃N / CH₂Cl₂

6: 94 percent / Pd(OAc)2 / acetonitrile

7: 93 percent / NaBH₄, CeCl₃ / methanol

8: 93 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂

9: 95 percent / TiCl₄, Zn / tetrahydrofuran

10: 93 percent / pyridine

11: 76 percent / Li, liq. NH₃ / ethanol

12: pyridine

13: 2.) NaCN / 1.) DMF; 2.) DMSO

15: lithium aluminum hydride / tetrahydrofuran

16: (COCl)2, DMSO, Et₃N / CH₂Cl₂

17: 93 percent / benzene

18: 75 percent / lithium aluminium hydride / tetrahydrofuran

With pyridine; palladium diacetate; sodium tetrahydroborate; lithium aluminium tetrahydride; cerium(III) chloride; oxalyl dichloride; sodium cyanide; ammonia; hydrogen; titanium tetrachloride; lithium; dimethyl sulfoxide; triethylamine; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; acetonitrile; benzene;

DOI:10.1039/c39880000354

upstream raw materials:

ceroplastol II 3,5-dinitrobenzoate

ethyl albolate

(R)-2-((Z)-(3S,3aR,6aS,10aS)-6,9,10a-Trimethyl-1,2,3,3a,4,6a,7,8,10,10a-decahydro-dicyclopenta[a,d]cycloocten-3-yl)-propan-1-ol

(S)-4-((Z)-(3R,3aR,6aS,10aS)-6,9,10a-Trimethyl-1,2,3,3a,4,6a,7,8,10,10a-decahydro-dicyclopenta[a,d]cycloocten-3-yl)-pentan-1-ol

Downstream raw materials:

ceroplastol II 3,5-dinitrobenzoate