2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester
CAS No.:596092-49-8
Molecular Formula:C₃₂H₄₄O₅Si
Molecular Weight:536.784
Hs Code.:

2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester

Synonyms:

Suppliers and Price of 2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester

There total 3 articles about 2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 136032-73-0,127251-09-6
4-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-L-threitol

: 596092-49-8
2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 91 percent / oxalyl chloride; DMSO / CH₂Cl₂ / 0.58 h / -78 °C

2.1: n-BuLi / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 1 h / -78 °C

2.2: 53 percent / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 2 h / -78 °C

3.1: pyridine; DMAP / CH₂Cl₂ / 12 h / Heating

With pyridine; dmap; n-butyllithium; oxalyl dichloride; dimethyl sulfoxide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; dichloromethane;
DOI:10.1021/ol034823f

Reference yield:

: 101331-92-4
4-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-L-threose

: 596092-49-8
2,2-Dimethyl-propionic acid (E)-(S)-1-[(4S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-penta-2,4-dienyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 1 h / -78 °C

1.2: 53 percent / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 2 h / -78 °C

2.1: pyridine; DMAP / CH₂Cl₂ / 12 h / Heating

With pyridine; dmap; n-butyllithium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; dichloromethane;
DOI:10.1021/ol034823f