METHYL PYRIMIDIN-2-YL ETHER

Base Information

• Chemical Name: METHYL PYRIMIDIN-2-YL ETHER
• CAS No.: 931-63-5
• Molecular Formula: C5H6 N2 O
• Molecular Weight: 110.115
• Hs Code.: 2933599090
• Mol file: 931-63-5.mol

Synonyms:2-Methoxypyrimidine;NSC 165557

Chemical Property of METHYL PYRIMIDIN-2-YL ETHER

Chemical Property:

• Vapor Pressure: 0.747mmHg at 25°C
• Melting Point: 280-290 °C (decomp)
• Boiling Point: 190.5°Cat760mmHg
• PKA: 1.16±0.13(Predicted)
• Flash Point: 68°C
• PSA: 35.01000
• Density: 1.102g/cm³
• LogP: 0.48520
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

95% ^*data from raw suppliers

2-Methoxypyrimidine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL PYRIMIDIN-2-YL ETHER

There total 1 articles about METHYL PYRIMIDIN-2-YL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + Pyrimidin-2(1H)-one (557-01-7) → 1-methyl-1H-pyrimidin-2-one (3739-81-9) + 2-methoxypyrimidine (931-63-5)

Guidance literature:

With diethyl ether;

Reference yield: 97.0%

2-methoxypyrimidine (931-63-5) + acetyl chloride (75-36-5) → C7H8N2O2 (1056174-56-1)

Guidance literature:

With cetyltrimethylammonim bromide; cetyltrimethylammonium chloride; In 1,2-dichloro-ethane; at 70 ℃; for 0.0833333h; Microwave irradiation; Micellar solution;

DOI:10.1016/j.tetlet.2013.04.075

Reference yield: 74.0%

2-methoxypyrimidine (931-63-5) + chlorophosphoric acid diphenyl ester (2524-64-3) → diphenyl (2-pyrimidyl) phosphate

Guidance literature:

In para-xylene; for 9h; Heating;

upstream raw materials:

diazomethane

Pyrimidin-2(1H)-one

Downstream raw materials:

2-pyrimidinylhydrazine

α-phenyl-2-pyrimidinylacetonitrile

5-hydroxy-2-methoxypyrimidine

1-methoxy-2-oxo-1,2-dihydropyrimidine