2-[(2-Chloro-1H-benzimidazol-6-yl)amino]benzoic acid

Base Information

Chemical Name:2-[(2-Chloro-1H-benzimidazol-6-yl)amino]benzoic acid
CAS No.:203302-76-5
Molecular Formula:C₁₄H₁₀ClN₃O₂
Molecular Weight:287.705
Hs Code.:
DSSTox Substance ID:DTXSID301217344

Synonyms:SCHEMBL17786361;DTXSID301217344;2-[(2-Chloro-1H-benzimidazol-6-yl)amino]benzoic acid;203302-76-5

Suppliers and Price of 2-[(2-Chloro-1H-benzimidazol-6-yl)amino]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[(2-Chloro-1H-benzimidazol-6-yl)amino]benzoic acid

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:287.0461543
Heavy Atom Count:20
Complexity:368

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)O)NC2=CC3=C(C=C2)N=C(N3)Cl

Technology Process of 2-[(2-Chloro-1H-benzimidazol-6-yl)amino]benzoic acid

There total 3 articles about 2-[(2-Chloro-1H-benzimidazol-6-yl)amino]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 203302-73-2
2-chloro-1H-benzo[d]imidazol-5-amine

: 88-65-3
2-bromobenzoic-acid

: 203302-76-5
N-(2-chlorobenzimidazol-5-yl)anthranilic acid

Guidance literature:: With copper; potassium carbonate; In butanone; for 3h; Heating; Irradiation;
DOI:10.1002/jhet.5570340623

Reference yield:

: 4857-06-1
2-chloro-1H-benzoimidazole

: 203302-76-5
N-(2-chlorobenzimidazol-5-yl)anthranilic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / conc. HNO₃, conc. H₂SO₄ / 1 h / 10 °C

2: 84 percent / stannous chloride dihydrate, conc. HCl / 4 h / 100 °C

3: 36 percent / K₂CO₃, Cu / butan-2-one / 3 h / Heating; Irradiation

With hydrogenchloride; sulfuric acid; nitric acid; copper; potassium carbonate; tin(ll) chloride; In butanone;
DOI:10.1002/jhet.5570340623

Reference yield:

: 5955-72-6
2-chloro-5-nitro-1H-benzo[d]imidazole

: 203302-76-5
N-(2-chlorobenzimidazol-5-yl)anthranilic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / stannous chloride dihydrate, conc. HCl / 4 h / 100 °C

2: 36 percent / K₂CO₃, Cu / butan-2-one / 3 h / Heating; Irradiation

With hydrogenchloride; copper; potassium carbonate; tin(ll) chloride; In butanone;
DOI:10.1002/jhet.5570340623