Etoposide impurity J [EP]

Base Information

Chemical Name:Etoposide impurity J [EP]
CAS No.:118356-05-1
Molecular Formula:C₂₂H₂₂O₈
Molecular Weight:414.412
Hs Code.:
UNII:UY5BXI2HZ5
ChEMBL ID:CHEMBL154358

Synonyms:Etoposide impurity J [EP];118356-05-1;UY5BXI2HZ5;(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5-methoxy-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one;(5R,5aR,8aR,9S)-5-(4-Hydroxy-3,5-dimethoxyphenyl)-9-methoxy-5,8,8a,9-tetrahydro(2)benzofuro(5,6-f)(1,3)benzodioxol-6(5ah)-one;UNII-UY5BXI2HZ5;MLS000697660;CHEMBL154358;Deglucopyranosyl Methoxy Etoposide;HMS2220B20;SMR000445564;ETOPOSIDE IMPURITY J [EP IMPURITY];5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-METHOXY-FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE, (5R-(5.ALPHA.,5A.BETA.,8A.ALPHA.,9.BETA.))-;5,8,8a,9-Tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-methoxy-furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5ah)-one, (5R-(5alpha,5abeta,8aalpha,9beta))-;FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-METHOXY-, (5R-(5.ALPHA.,5A.BETA.,8A.ALPHA.,9.BETA.))-;Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5ah)-one, 5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-methoxy-, (5R-(5alpha,5abeta,8aalpha,9beta))-

Suppliers and Price of Etoposide impurity J [EP]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Etoposide impurity J [EP]

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:414.13146766
Heavy Atom Count:30
Complexity:629

Purity/Quality:: HPLC ≥ 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1C2COC(=O)C2C(C3=CC4=C(C=C13)OCO4)C5=CC(=C(C(=C5)OC)O)OC
Isomeric SMILES:CO[C@H]1[C@H]2COC(=O)[C@@H]2[C@@H](C3=CC4=C(C=C13)OCO4)C5=CC(=C(C(=C5)OC)O)OC

Technology Process of Etoposide impurity J [EP]

There total 1 articles about Etoposide impurity J [EP] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 518-28-5
podofilox

: 118356-05-1
4'-demethylepipodophyllotoxin 4-methyl ether

Guidance literature:: With hydrogen bromide; barium carbonate; Yield given. Multistep reaction; 1.) CH₂Cl₂, 0 deg C, 20 h 2.) 2 h;
DOI:10.1021/jm00123a016