3-bromo-7,8-difluoroquinoline

Base Information

• Chemical Name: 3-bromo-7,8-difluoroquinoline
• CAS No.: 1686108-69-9
• Molecular Formula: C₉H₄BrF₂N
• Molecular Weight: 244.038
• Mol file: 1686108-69-9.mol

Synonyms:

Chemical Property of 3-bromo-7,8-difluoroquinoline

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

3-Bromo-7,8-difluoroquinoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-bromo-7,8-difluoroquinoline

There total 1 articles about 3-bromo-7,8-difluoroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

7,8-Difluoroquinoline (145241-76-5) → 3-bromo-7,8-difluoroquinoline (1686108-69-9)

Guidance literature:

With N-Bromosuccinimide; acetic acid; at 110 ℃; for 12h;

Reference yield:

3-bromo-7,8-difluoroquinoline (1686108-69-9) → 3-amino-7,8-difluoroquinoline (318685-32-4)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium diacetate; caesium carbonate / 1,4-dioxane / 4 h / 90 °C

2: hydrogenchloride / methanol / 14 h / 20 °C

With hydrogenchloride; palladium diacetate; caesium carbonate; In 1,4-dioxane; methanol;

upstream raw materials:

7,8-Difluoroquinoline

Downstream raw materials:

3-amino-7,8-difluoroquinoline