5-oxo-2'-phenyl-L-prolinohydrazide

Base Information

• Chemical Name: 5-oxo-2'-phenyl-L-prolinohydrazide
• CAS No.: 26275-69-4
• Molecular Formula: C11H13 N3 O2
• Molecular Weight: 219.243
• Mol file: 26275-69-4.mol

Synonyms:Proline, 5-oxo-, 2-phenylhydrazide (8CI)

Chemical Property of 5-oxo-2'-phenyl-L-prolinohydrazide

Chemical Property:

• PSA: 70.23000
• LogP: 1.20100

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-oxo-2'-phenyl-L-prolinohydrazide

There total 5 articles about 5-oxo-2'-phenyl-L-prolinohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Boc-Gln-OH (13726-85-7) → 5-oxo-2'-phenyl-L-prolinohydrazide (26275-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 53.5 percent / papain / H₂O / 24 h / 38 °C / acetate buffer, pH 4.5, ethylenediaminetetracetic acid, cysteine hydrochloride

2: 1. CF₃COOH; 2. papain / 2. aq. NaOH, pH 7.5, 37 deg C, 2 h

With trifluoroacetic acid; papain; In water;

Reference yield:

phenylhydrazine (100-63-0) → 5-oxo-2'-phenyl-L-prolinohydrazide (26275-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 53.5 percent / papain / H₂O / 24 h / 38 °C / acetate buffer, pH 4.5, ethylenediaminetetracetic acid, cysteine hydrochloride

2: 1. CF₃COOH; 2. papain / 2. aq. NaOH, pH 7.5, 37 deg C, 2 h

With trifluoroacetic acid; papain; In water;

Reference yield:

glutamic acid α-phenylhydrazide γ-methylamide (101925-04-6) → 5-oxo-2'-phenyl-L-prolinohydrazide (26275-69-4)

Guidance literature:

With papain; In water; at 37 ℃; for 24h; Product distribution; pH 6.9;

upstream raw materials:

glutamic acid α-phenylhydrazide γ-methylamide

tert-butyloxycarbonylglutamine phenylhydrazide

glutamine phenylhydrazide

Boc-Gln-OH

Refernces