2,2-difluoro-4,6-di-p-tolyl-2H-1λ³,3,2λ⁴-dioxaborinine

Base Information

• Chemical Name: 2,2-difluoro-4,6-di-p-tolyl-2H-1λ³,3,2λ⁴-dioxaborinine
• CAS No.: 161649-49-6
• Molecular Formula: C₁₇H₁₅BF₂O₂
• Molecular Weight: 300.113
• Mol file: 161649-49-6.mol

Synonyms:

Chemical Property of 2,2-difluoro-4,6-di-p-tolyl-2H-1λ³,3,2λ⁴-dioxaborinine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-difluoro-4,6-di-p-tolyl-2H-1λ³,3,2λ⁴-dioxaborinine

There total 3 articles about 2,2-difluoro-4,6-di-p-tolyl-2H-1λ³,3,2λ⁴-dioxaborinine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1,3-bis(p-methylphenyl)-1,3-propanedione (3594-36-3) + boron trifluoride diethyl etherate (109-63-7) → 2,2-difluoro-4,6-di-p-tolyl-2H-1λ3,3,2λ4-dioxaborinine (161649-49-6)

Guidance literature:

In toluene; for 1h; Reflux;

DOI:10.1039/c6nj02923j

Reference yield: 84.0%

1,3-di(4-methylphenyl)propane-1,3-dione (62375-98-8) → 2,2-difluoro-4,6-di-p-tolyl-2H-1λ3,3,2λ4-dioxaborinine (161649-49-6)

Guidance literature:

In benzene; at 20 ℃; for 15h; Inert atmosphere;

DOI:10.1002/chem.201503132

Reference yield:

4-methyl-benzoic acid methyl ester (99-75-2) + para-methylacetophenone (122-00-9) → 2,2-difluoro-4,6-di-p-tolyl-2H-1λ3,3,2λ4-dioxaborinine (161649-49-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / 24.5 h / 20 - 70 °C

2: benzene / 15 h / 20 °C / Inert atmosphere

With sodium hydride; In tetrahydrofuran; mineral oil; benzene; 1: |Claisen Condensation;

DOI:10.1002/chem.201503132

upstream raw materials:

4-methyl-benzoic acid methyl ester

para-methylacetophenone

1,3-di(4-methylphenyl)propane-1,3-dione

1,3-bis(p-methylphenyl)-1,3-propanedione

Refernces

• 1、 Costa, Letícia D.,Guieu, Samuel,Rocha, Jo?o,Silva, Artur M. S.,Tomé, Augusto C.. "Porphyrin-boron diketonate dyads". supporting information. p. 2186 - 2192. Retrieved 2017/03/10.