2,4-dihydroxy-5-nitrobenzoic acid

Base Information

• Chemical Name: 2,4-dihydroxy-5-nitrobenzoic acid
• CAS No.: 13722-96-8
• Molecular Formula: C7H5NO6
• Molecular Weight: 199.12
• Hs Code.: 2918290000
• Mol file: 13722-96-8.mol

Synonyms:4-Nitro-6-carboxy-resorcin;Benzoic acid,2,4-dihydroxy-5-nitro;5-Nitro-2,4-dihydroxy-benzoesaeure;2,4-dihydroxy-5-nitro-benzoic acid;β-Resorcylic acid, 5-nitro-;2,4-Dihydroxy-5-nitro-benzoesaeure;

Chemical Property of 2,4-dihydroxy-5-nitrobenzoic acid

Chemical Property:

• PSA: 123.58000
• LogP: 1.22740
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4-Dihydroxy-5-nitrobenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-dihydroxy-5-nitrobenzoic acid

There total 8 articles about 2,4-dihydroxy-5-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

4-hydroxysalicylic acid (89-86-1) → 2,4-dihydroxy-5-nitrobenzoic acid (13722-96-8)

Guidance literature:

With nitric acid; acetic acid; at 20 ℃; for 12h;

DOI:10.1021/jo050798a

Reference yield: 30.0%

4-hydroxysalicylic acid (89-86-1) → 4-nitroresorcinol (3163-07-3) + 2,4-dihydroxy-5-nitrobenzoic acid (13722-96-8)

Guidance literature:

With ammonium cerium(IV) nitrate; In acetonitrile; at 80 - 90 ℃; for 0.25h;

Reference yield:

4-hydroxysalicylic acid (89-86-1) → styphnic acid (82-71-3) + 2,4-dihydroxy-5-nitrobenzoic acid (13722-96-8)

Guidance literature:

With nitric acid;

upstream raw materials:

4-hydroxysalicylic acid

4-hydroxy-5-nitrosalicylate

nitric acid

2,4-dihydroxy-5-nitro-benzoic acid methyl ester

Downstream raw materials:

2,4-dimethoxy-5-nitro-benzoic acid methyl ester

2,4-diethoxy-5-nitro-benzoic acid ethyl ester

2,4-dihydroxy-5-nitro-benzoic acid methyl ester

4-nitroresorcinol

Refernces

• 1、 -. "Preparation method for 5-amino-2,4-dihydroxybenzoic acid". Paragraph 0035; 0036; 0037; 0038; 0039; 0040; 0041-0043. . Retrieved 2019/04/26.
• 2、 -. "CAVITY-CONTAINING OLIGOMERS AND POLYMERS EFFECTIVE IN CRYOPRESERVATION". Paragraph 0033; 0116. . Retrieved 2019/06/09.