N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine

Base Information

Chemical Name:N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine
CAS No.:132844-51-0
Molecular Formula:C₁₅H₁₃F₃N₂O₂S
Molecular Weight:342.342
Hs Code.:
DSSTox Substance ID:DTXSID301162852

Synonyms:DTXSID301162852;N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine;132844-51-0

Suppliers and Price of N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:342.06498332
Heavy Atom Count:23
Complexity:508

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC1NC2=C(C=CC(=N2)S(=O)(=O)C3=CC=CC=C3)C(F)(F)F

Technology Process of N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine

There total 4 articles about N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55304-75-1
2,6-dichloro-3-(trifluoromethyl)pyridine

: 132844-51-0
N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine

Guidance literature:: Multi-step reaction with 3 steps

1: 1) NaH / 1) HMPA, 10 min, 25 deg C 2) 1 h, 100 deg C

2: 97 percent / m-chloroperoxybenzoic acid / CH₂Cl₂ / 24 h / 25 °C

3: 0.30 g / Et₃N / 8 h / 25 °C

With sodium hydride; triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1002/jhet.5570270602

Reference yield:

: 132844-49-6
2,6-Bis(phenylthio)-3-(trifluoromethyl)pyridine

: 132844-51-0
N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / m-chloroperoxybenzoic acid / CH₂Cl₂ / 24 h / 25 °C

2: 0.30 g / Et₃N / 8 h / 25 °C

With triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1002/jhet.5570270602

Reference yield:

: 108-98-5
thiophenol

: 132844-51-0
N-Cyclopropyl-6-(phenylsulfonyl)-3-(trifluoromethyl)-2-pyridinamine

Guidance literature:: Multi-step reaction with 3 steps

1: 1) NaH / 1) HMPA, 10 min, 25 deg C 2) 1 h, 100 deg C

2: 97 percent / m-chloroperoxybenzoic acid / CH₂Cl₂ / 24 h / 25 °C

3: 0.30 g / Et₃N / 8 h / 25 °C

With sodium hydride; triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1002/jhet.5570270602