Tandamine

Base Information

Chemical Name:Tandamine
CAS No.:42408-80-0
Molecular Formula:C₁₈H₂₆N₂S
Molecular Weight:302.484
Hs Code.:
NSC Number:305532
UNII:6L5FH5A43E,D38V2K62U7,P8Q86YNB85
DSSTox Substance ID:DTXSID70866094
Nikkaji Number:J16.877G
Wikipedia:Tandamine
Wikidata:Q7682407
NCI Thesaurus Code:C152506
Metabolomics Workbench ID:152227
ChEMBL ID:CHEMBL2110652
Mol file:42408-80-0.mol

Synonyms:1-(2-(dimethylamino)ethyl)-9-ethyl- 1,3,4,9-tetrahydro-1-methylthiopyrano(3,4-b)indole;AY 23946;tandamine;tandamine hydrochloride, (+)-isomer;tandamine hydrochloride, (+-)-isomer;tandamine hydrochloride, (-)-isomer;tandamine monohydrochloride

Suppliers and Price of Tandamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TANDAMINE 95.00%
5MG
$ 500.64

Total 1 raw suppliers

Chemical Property of Tandamine

Chemical Property:

Vapor Pressure:5.61E-08mmHg at 25°C
Boiling Point:441°Cat760mmHg
Flash Point:220.5°C
PSA：33.47000
Density:1.1g/cm³
LogP:4.11740
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:302.18167001
Heavy Atom Count:21
Complexity:359

Purity/Quality:

99% ^*data from raw suppliers

TANDAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C2=CC=CC=C2C3=C1C(SCC3)(C)CCN(C)C
Uses Antidepressant.

Technology Process of Tandamine

There total 11 articles about Tandamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium 1-ethylindole-3-ethyl thiosulfate: sodium 1-ethylindole-3-ethyl thiosulfate

: 59127-87-6
2-(1-ethyl-1H-indol-3-yl)ethanol

: 2543-57-9
1-Dimethylamino-3-butanon

potassium 1-ethylindole-3-ethyl thiosulfate: potassium 1-ethylindole-3-ethyl thiosulfate

: 42408-80-0,62481-65-6,62481-67-8
tandamine

Guidance literature:: With sodium hydroxide; p-toluenesulfonic acid monohydrate; In water; toluene;

Reference yield:

(1-methyl-1,3,4,9-tetrahydro-thiopyrano[3,4-b]indol-1-yl)-acetic acid: 41339-53-1
(1-methyl-1,3,4,9-tetrahydro-thiopyrano[3,4-b]indol-1-yl)-acetic acid

: 42408-80-0,62481-48-5,62481-65-6,62481-67-8
[2-(9-ethyl-1-methyl-1,3,4,9-tetrahydro-thiopyrano[3,4-b]indol-1-yl)-ethyl]-dimethyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: (i) Et₃N, THF, (ii) ClCO₂Et, (iii) /BRN= 605257/, H₂O

2: LiAlH₄ / tetrahydrofuran; diethyl ether

3: (i) NaH, DMF, (ii) /BRN= 1209224/

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;

Reference yield:

(1-methyl-1,3,4,9-tetrahydro-thiopyrano[3,4-b]indol-1-yl)-acetic acid: 41339-53-1
(1-methyl-1,3,4,9-tetrahydro-thiopyrano[3,4-b]indol-1-yl)-acetic acid

: 42408-80-0,62481-48-5,62481-65-6,62481-67-8
[2-(9-ethyl-1-methyl-1,3,4,9-tetrahydro-thiopyrano[3,4-b]indol-1-yl)-ethyl]-dimethyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: (i) Et₃N, THF, (ii) ClCO₂Et, (iii) /BRN= 605257/, H₂O

2: LiAlH₄ / tetrahydrofuran; diethyl ether

3: (i) NaH, DMF, (ii) /BRN= 1209224/

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;