4-Benzamido-N-phenylbenzamide

Base Information

• Chemical Name: 4-Benzamido-N-phenylbenzamide
• CAS No.: 13755-08-3
• Molecular Formula: C20H16N2O2
• Molecular Weight: 316.359
• DSSTox Substance ID: DTXSID20578716
• Wikidata: Q82469023
• Mol file: 13755-08-3.mol

Synonyms:4-Benzamido-N-phenylbenzamide;13755-08-3;4-benzamido-N-phenyl-benzamide;SCHEMBL26953087;DTXSID20578716;AKOS017099138;Z57690925

Chemical Property of 4-Benzamido-N-phenylbenzamide

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 316.121177757
• Heavy Atom Count: 24
• Complexity: 417

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)C(=O)NC3=CC=CC=C3

Technology Process of 4-Benzamido-N-phenylbenzamide

There total 6 articles about 4-Benzamido-N-phenylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

4-iodo-N-phenylbenzamide (17370-92-2) + benzamide (55-21-0,27208-38-4) → 4-benzamido-N-phenylbenzamide (13755-08-3)

Guidance literature:

With copper(I) thiophene-2-carboxylate; sodium t-butanolate; In dimethyl sulfoxide; at 110 ℃; for 10h; Inert atmosphere;

DOI:10.1002/aoc.3080

Reference yield:

4-iodobenzamide (3956-07-8) → 4-benzamido-N-phenylbenzamide (13755-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(ll) sulfate pentahydrate; sodium ascorbate; sodium t-butanolate / dimethyl sulfoxide / 7 h / 100 °C

2: copper(ll) sulfate pentahydrate; sodium ascorbate; sodium t-butanolate / dimethyl sulfoxide / 12 h / 130 °C

With copper(ll) sulfate pentahydrate; sodium ascorbate; sodium t-butanolate; In dimethyl sulfoxide;

DOI:10.1016/j.tet.2013.07.073

Reference yield:

4-amino-benzoic acid anilide (782-45-6) + benzoyl chloride (98-88-4) → 4-benzamido-N-phenylbenzamide (13755-08-3)

Guidance literature:

With benzene;

DOI:10.1021/ja01226a601

upstream raw materials:

4-amino-benzoic acid anilide

benzoyl chloride

4-nitrobenzanilide

4-iodo-N-phenylbenzamide