Technology Process of Ni(II)-3,13-bis(ethoxycarbonyl)-2,12-dimesityl-5-methoxy-8,8,18,18-tetramethylbacteriochlorin
There total 8 articles about Ni(II)-3,13-bis(ethoxycarbonyl)-2,12-dimesityl-5-methoxy-8,8,18,18-tetramethylbacteriochlorin which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3,13-bis(ethoxycarbonyl)-2,12-dimesityl-5-methoxy-8,8,18,18-tetramethylbacteriochlorin;
With
sodium hydride;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
nickel dichloride;
In
tetrahydrofuran;
at 60 ℃;
for 3h;
DOI:10.1021/ic301262k
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: sodium hydride / diethyl ether; dimethyl sulfoxide; mineral oil; tetrahydrofuran / 2.5 h / Inert atmosphere
2.1: trichlorophosphate / dichloromethane / 19 h / 0 - 20 °C / Inert atmosphere
2.2: 0 °C / Inert atmosphere
3.1: propylamine; acetic acid / tetrahydrofuran; methanol / 3.25 h / 0 - 20 °C / Inert atmosphere
4.1: silica gel; sodium tetrahydroborate / chloroform; isopropyl alcohol / 0.67 h
5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 7 h / 20 °C / Inert atmosphere
6.1: sodium methylate / tetrahydrofuran / 1.25 h / 20 °C / Inert atmosphere
6.2: 20 °C / pH 6 / Inert atmosphere
7.1: trimethylsilyl trifluoromethanesulfonate; 2,6-di-tert-butylphenol / dichloromethane / 19 h / 20 °C
8.1: sodium hydride / tetrahydrofuran / 1 h / 20 °C
8.2: 3 h / 60 °C
With
propylamine; sodium tetrahydroborate; 2,6-di-tert-butylphenol; trimethylsilyl trifluoromethanesulfonate; sodium methylate; silica gel; sodium hydride; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; chloroform; dimethyl sulfoxide; isopropyl alcohol; mineral oil;
2.1: |Vilsmeier Reaction / 3.1: |Henry Nitro Aldol Condensation / 5.1: |Michael Addition / 6.2: |McMurry Reaction;
DOI:10.1021/ic301262k
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: trichlorophosphate / dichloromethane / 19 h / 0 - 20 °C / Inert atmosphere
1.2: 0 °C / Inert atmosphere
2.1: propylamine; acetic acid / tetrahydrofuran; methanol / 3.25 h / 0 - 20 °C / Inert atmosphere
3.1: silica gel; sodium tetrahydroborate / chloroform; isopropyl alcohol / 0.67 h
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 7 h / 20 °C / Inert atmosphere
5.1: sodium methylate / tetrahydrofuran / 1.25 h / 20 °C / Inert atmosphere
5.2: 20 °C / pH 6 / Inert atmosphere
6.1: trimethylsilyl trifluoromethanesulfonate; 2,6-di-tert-butylphenol / dichloromethane / 19 h / 20 °C
7.1: sodium hydride / tetrahydrofuran / 1 h / 20 °C
7.2: 3 h / 60 °C
With
propylamine; sodium tetrahydroborate; 2,6-di-tert-butylphenol; trimethylsilyl trifluoromethanesulfonate; sodium methylate; silica gel; sodium hydride; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; isopropyl alcohol;
1.1: |Vilsmeier Reaction / 2.1: |Henry Nitro Aldol Condensation / 4.1: |Michael Addition / 5.2: |McMurry Reaction;
DOI:10.1021/ic301262k
