C₂₆H₂₃FN₆O₃S₂

Base Information

Chemical Name:C₂₆H₂₃FN₆O₃S₂
CAS No.:1374036-37-9
Molecular Formula:C₂₆H₂₃FN₆O₃S₂
Molecular Weight:550.637
Hs Code.:

C<sub>26</sub>H<sub>23</sub>FN<sub>6</sub>O<sub>3</sub>S<sub>2</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₆H₂₃FN₆O₃S₂

Chemical Property:

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Technology Process of C₂₆H₂₃FN₆O₃S₂

There total 6 articles about C₂₆H₂₃FN₆O₃S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₁₉N₅O₂S₂

: 404-71-7
1-fluoro-3-isocyanatobenzene

: 1374036-37-9
C₂₆H₂₃FN₆O₃S₂

Guidance literature:: With 4-methyl-morpholine; In N,N-dimethyl-formamide; at -20 ℃;
DOI:10.1016/j.bmcl.2012.03.035

Reference yield:

: 832695-08-6
tert-butyl 4-(4-amino-7-iodothieno[3,2-c]pyridin-3-yl)phenylcarbamate

: 1374036-37-9
C₂₆H₂₃FN₆O₃S₂

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / tetrahydrofuran; methanol; water / 80 °C

3: 4-methyl-morpholine / N,N-dimethyl-formamide / -20 °C

With 4-methyl-morpholine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; trifluoroacetic acid; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; 2: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.03.035

Reference yield:

: 799293-85-9
3-bromo-4-amino-[3,2-c]-thienopyridine

: 1374036-37-9
C₂₆H₂₃FN₆O₃S₂

Guidance literature:: Multi-step reaction with 5 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,2-dimethoxyethane; water / 90 °C

2: N-iodo-succinimide / N,N-dimethyl-formamide

3: trifluoroacetic acid

4: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / tetrahydrofuran; methanol; water / 80 °C

5: 4-methyl-morpholine / N,N-dimethyl-formamide / -20 °C

With 4-methyl-morpholine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; N-iodo-succinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; trifluoroacetic acid; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; 1: Suzuki coupling / 4: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.03.035