Propargyl-PEG3-Bromide

Base Information

Chemical Name:Propargyl-PEG3-Bromide
CAS No.:203740-63-0
Molecular Formula:C₉H₁₅BrO₃
Molecular Weight:251.12
Hs Code.:2942000090
Mol file:203740-63-0.mol

Synonyms:

Suppliers and Price of Propargyl-PEG3-Bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
Propargyl-PEG3-bromide 98%
250 MG
$ 350.00

BroadPharm
Propargyl-PEG3-bromide 98%
1 G
$ 890.00

Acrotein
Propargyl-PEG3-Br 97%
1g
$ 412.50

Total 8 raw suppliers

Chemical Property of Propargyl-PEG3-Bromide

Chemical Property:

Boiling Point:287.8±25.0 °C(Predicted)
Density:1.300±0.06 g/cm3(Predicted)
Solubility.:Soluble in DMSO, DCM, DMF

Purity/Quality:

98%,99%, ^*data from raw suppliers

Propargyl-PEG3-bromide 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Propargyl-PEG3-bromide comprises a propargyl group and a bromide group. The propargyl group reacts with azide-bearing compounds or biomolecules in Click Chemistry to yield a stable triazole linkage; copper will be needed as a catalyst.

Technology Process of Propargyl-PEG3-Bromide

There total 3 articles about Propargyl-PEG3-Bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 208827-90-1
O-propargyl triethylene glycol

: 203740-63-0,2055105-25-2
1-bromo-2-[2-[2-(prop-2-yn-1-yloxy)ethoxy]ethoxy]ethane

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 16.3333h; Inert atmosphere;

Reference yield: 9.2%

: 31255-10-4
1,2-bis-(2-bromo-ethoxy)-ethane

: 107-19-7
propargyl alcohol

: 203740-63-0,2055105-25-2
1-bromo-2-[2-[2-(prop-2-yn-1-yloxy)ethoxy]ethoxy]ethane

: 126422-58-0
α,ω-bis(O-propargyl)triethylene glycol

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 40 ℃; for 18h;
DOI:10.1002/prac.19983400207

Reference yield:

: 112-27-6
2,2'-[1,2-ethanediylbis(oxy)]bisethanol

: 203740-63-0,2055105-25-2
1-bromo-2-[2-[2-(prop-2-yn-1-yloxy)ethoxy]ethoxy]ethane

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 0 °C

1.2: 3 h / 0 - 20 °C / Inert atmosphere

2.1: triphenylphosphine; carbon tetrabromide / tetrahydrofuran / 16.33 h / 0 - 20 °C / Inert atmosphere

With carbon tetrabromide; sodium hydride; triphenylphosphine; In tetrahydrofuran; mineral oil;