1-phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethanol

Base Information

Chemical Name:1-phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethanol
CAS No.:211947-81-8
Molecular Formula:C₁₉H₂₁NO
Molecular Weight:279.382
Hs Code.:
DSSTox Substance ID:DTXSID301333205
ChEMBL ID:CHEMBL1482723

Synonyms:1-phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethanol;MLS001233676;CHEMBL1482723;DTXSID301333205;HMS2903M20;AKOS034158779;SMR000596139;Z31358608;211947-81-8

Suppliers and Price of 1-phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethanol

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:279.162314293
Heavy Atom Count:21
Complexity:340

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CC=C1C2=CC=CC=C2)CC(C3=CC=CC=C3)O

Technology Process of 1-phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethanol

There total 3 articles about 1-phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95278-62-9
1-phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethanone

: 211947-81-8
(+/-)-1-(2'-hydroxy-2'-phenyl)ethyl-4-phenyl-1,2,5,6-tetrahydropyridine

Guidance literature:: With sodium tetrahydroborate; In methanol; Yield given; Ambient temperature;
DOI:10.1002/prac.19983400511

Reference yield:

: 43064-12-6
1,2,3,6-tetrahydro-4-phenylpyridine hydrochloride

: 211947-81-8
(+/-)-1-(2'-hydroxy-2'-phenyl)ethyl-4-phenyl-1,2,5,6-tetrahydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 40 °C

2: NaBH₄ / methanol / Ambient temperature

With sodium tetrahydroborate; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/prac.19983400511

Reference yield:

: 70-11-1
α-bromoacetophenone

: 211947-81-8
(+/-)-1-(2'-hydroxy-2'-phenyl)ethyl-4-phenyl-1,2,5,6-tetrahydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 40 °C

2: NaBH₄ / methanol / Ambient temperature

With sodium tetrahydroborate; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/prac.19983400511