Technology Process of Ethyl indenestrol A
There total 8 articles about Ethyl indenestrol A which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 25 ℃;
for 0.25h;
DOI:10.1021/jm050226i
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 11.553 g / 5 h / 60 - 100 °C
2.1: NaH / tetrahydrofuran; hexane / 3 h / 25 °C
2.2: 100 percent / tetrahydrofuran; hexane / 14 h / 25 °C
3.1: 55 percent / BBr3 / CH2Cl2 / 7.5 h / -78 - 25 °C
4.1: 81 percent / imidazole / dimethylformamide / 3.5 h / 25 °C
5.1: n-BuLi / diethyl ether; hexane / 0.33 h / -78 - 0 °C
5.2: 38 percent / diethyl ether; hexane / -78 - 25 °C
6.1: 22 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.25 h / 25 °C
With
1H-imidazole; n-butyllithium; tetrabutyl ammonium fluoride; boron tribromide; sodium hydride;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm050226i
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 55 percent / BBr3 / CH2Cl2 / 7.5 h / -78 - 25 °C
2.1: 81 percent / imidazole / dimethylformamide / 3.5 h / 25 °C
3.1: n-BuLi / diethyl ether; hexane / 0.33 h / -78 - 0 °C
3.2: 38 percent / diethyl ether; hexane / -78 - 25 °C
4.1: 22 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.25 h / 25 °C
With
1H-imidazole; n-butyllithium; tetrabutyl ammonium fluoride; boron tribromide;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm050226i
