3,6-dimethoxy-4-phenylpyridazine

Base Information

• Chemical Name: 3,6-dimethoxy-4-phenylpyridazine
• CAS No.: 91392-56-2
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.239
• Mol file: 91392-56-2.mol

Synonyms:

Chemical Property of 3,6-dimethoxy-4-phenylpyridazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-dimethoxy-4-phenylpyridazine

There total 2 articles about 3,6-dimethoxy-4-phenylpyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3,6-dimethoxypyridazine (4603-59-2) + iodobenzene (591-50-4) → 3,6-dimethoxy-4-phenylpyridazine (91392-56-2)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; zinc(II) chloride; In tetrahydrofuran; hexane; Product distribution; multistep; substrates diazines; lithiation by lithium tetramethylpiperidide or LDA; quantity of ZnCl₂; coupling of organozinc derivative with aryl halides: temperature 25-125 deg C, with/without sonication, quantity of Pd(PPh₃)4;

DOI:10.3987/com-98-s17

Reference yield:

→ 3,6-dimethoxy-4-phenylpyridazine (91392-56-2)

Guidance literature:

neben 1.6-Dihydro-3-methoxy-6-oxo-4-phenyl-pyridazin aus 1.) 4,5-Dihydro-3,6-di-methoxy-4-phenyl-pyridazin u.Br2 mit Na-Acetat in CHCl3, 2.) Na-Methylat in sd. Me.;

upstream raw materials:

3,6-dimethoxypyridazine

iodobenzene