Technology Process of 9-cis-9-demethylretinal
There total 15 articles about 9-cis-9-demethylretinal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 96 percent / NaBH4 / ethanol / 0.08 h / Ambient temperature
2: 95 percent / methanol / 24 h
3: 1.6 M BuLi / tetrahydrofuran; hexane / 1.) 1 h, -60 deg C; 2.) 2 h to RT
4: 96 percent / 10 percent KOH / methanol / 1 h
5: MnO2 / CH2Cl2
6: acetonitrile / Irradiation; further solvent
With
manganese(IV) oxide; potassium hydroxide; sodium tetrahydroborate; n-butyllithium;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.6 M BuLi / tetrahydrofuran; hexane / 1.) 1 h, -60 deg C; 2.) 2 h to RT
2: 96 percent / 10 percent KOH / methanol / 1 h
3: MnO2 / CH2Cl2
4: acetonitrile / Irradiation; further solvent
With
manganese(IV) oxide; potassium hydroxide; n-butyllithium;
In
tetrahydrofuran; methanol; hexane; dichloromethane; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 95 percent / methanol / 24 h
2: 1.6 M BuLi / tetrahydrofuran; hexane / 1.) 1 h, -60 deg C; 2.) 2 h to RT
3: 96 percent / 10 percent KOH / methanol / 1 h
4: MnO2 / CH2Cl2
5: acetonitrile / Irradiation; further solvent
With
manganese(IV) oxide; potassium hydroxide; n-butyllithium;
In
tetrahydrofuran; methanol; hexane; dichloromethane; acetonitrile;
