Acetic acid,2-(4-methoxyphenyl)hydrazide

Base Information

• Chemical Name: Acetic acid,2-(4-methoxyphenyl)hydrazide
• CAS No.: 17473-78-8
• Molecular Formula: C9H12 N2 O2
• Molecular Weight: 180.206
• Mol file: 17473-78-8.mol

Synonyms:Aceticacid, 2-(p-methoxyphenyl)hydrazide (8CI); NSC 38543;N'-(4-Methoxyphenyl)acetohydrazide

Chemical Property of Acetic acid,2-(4-methoxyphenyl)hydrazide

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetic acid,2-(4-methoxyphenyl)hydrazide

There total 8 articles about Acetic acid,2-(4-methoxyphenyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

4-methoxyphenylhydrazine hydrochloride (19501-58-7) + acetic anhydride (108-24-7) → N’-(4-methoxyphenyl)acetohydrazide (17473-78-8)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 14h; Inert atmosphere;

DOI:10.1055/s-0032-1316877

Reference yield: 69.0%

acetic acid (64-19-7,77671-22-8) + 4-Methoxyphenylhydrazine (3471-32-7) → N’-(4-methoxyphenyl)acetohydrazide (17473-78-8)

Guidance literature:

at 20 - 80 ℃; for 1.5h; Inert atmosphere;

DOI:10.1002/anie.201207173

Reference yield: 58.0%

p-methoxybenzenediazonium (17333-79-8) + dimethylglyoxal (431-03-8) → butane-2,3-dione-mono-(4-methoxy-phenylhydrazone) (136953-50-9) + N’-(4-methoxyphenyl)acetohydrazide (17473-78-8)

Guidance literature:

With titanium(III) chloride; In acetic acid; for 0.666667h; Ambient temperature;

DOI:10.1021/jo00024a021

upstream raw materials:

acetic acid

4-Methoxyphenylhydrazine

p-methoxybenzenediazonium

dimethylglyoxal

Downstream raw materials:

N,N'-dimethyl-N'-(4-methoxyphenyl)acetohydrazide

1-(4-methoxyphenyl)-5-(p-tolyl)-1H-1,2,4-triazol-3-amine

2-(p-methoxyphenyl)-benzo[b]furan

6-hydroxy-4-methoxy-2-phenylbenzofuran