RBM1-77

Base Information

• Chemical Name: RBM1-77
• CAS No.: 97014-46-5
• Molecular Formula: C₁₈H₃₉NO
• Molecular Weight: 285.514
• Mol file: 97014-46-5.mol

Synonyms:

Chemical Property of RBM1-77

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of RBM1-77

There total 35 articles about RBM1-77 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Spinulosine 285 (109555-73-9) → spisulosine (97014-46-5,196497-48-0)

Guidance literature:

With sodium hydroxide; In dichloromethane; water;

DOI:10.1002/ejoc.200900828

Reference yield: 99.0%

dibenzyl 1-((2S,3R,E)-3-hydroxydodec-5-en-2-yl)hydrazine-1,2-dicarboxylate (1463439-99-7) → spisulosine (97014-46-5,196497-48-0)

Guidance literature:

With hydrogen; acetic acid; In methanol; at 20 ℃; for 8h; under 3102.97 Torr;

DOI:10.1039/c3ra43048k

Reference yield: 92.0%

(4S,5S)-4-methyl-5-pentadecyloxazolidin-2-one (1439377-20-4) → RBM1-77 (97014-46-5,196497-48-0)

Guidance literature:

With water; sodium hydroxide; In ethanol; for 2h; Reflux;

DOI:10.1021/jo400440z

upstream raw materials:

(S)-2-amino-octadecan-3-one; hydrobromide

tetrahydrofuran

diethyl ether

ethanol

Downstream raw materials:

D_s-threo-2-benzoylamino-octadecan-3-ol

Refernces

• 1、 Guan, Huashi,Jiang, Tao,Liu, Jiannan,Liu, Xuemeng,Wang, Xueting,Wu, Guanzhao,Yin, Ruijuan,Yu, Mingming,Yu, Rilei,Zhang, Yixuan. "Self-assembling nanoparticles of dually hydrophobic prodrugs constructed from camptothecin analogue for cancer therapy". supporting information. . Retrieved 2020/05/25.
• 2、 Silveira-Dorta, Gastón,Sousa, Inês J.,Fernandes, Miguel X.,Martín, Victor S.,Padrón, José M.. "Synthesis and identification of unprecedented selective inhibitors of CK1ε". . p. 308 - 317. Retrieved 2015/04/27.