cis-cyclohex-3-enyl-1,2-diamine dihydrochloride

Base Information

• Chemical Name: cis-cyclohex-3-enyl-1,2-diamine dihydrochloride
• CAS No.: 102312-67-4
• Molecular Formula: C₆H₁₂N₂*2ClH
• Molecular Weight: 185.097
• Mol file: 102312-67-4.mol

Synonyms:

Chemical Property of cis-cyclohex-3-enyl-1,2-diamine dihydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-cyclohex-3-enyl-1,2-diamine dihydrochloride

There total 9 articles about cis-cyclohex-3-enyl-1,2-diamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2,3,3a,4,7,7a-hexahydro-1H-benzimidazol-2-one (129884-35-1) → cis-cyclohex-3-enyl-1,2-diamine dihydrochloride (102312-67-4,105249-35-2,108796-57-2,118157-55-4)

Guidance literature:

With hydrogenchloride; at 100 ℃; for 0.0833333h; microwave irradiation;

DOI:10.1080/00397910701464951

Reference yield: 64.69%

maleic acid dichloroanhydride (22542-53-6) + buta-1,3-diene (106-99-0,130983-70-9,29406-96-0,9003-17-2) → rac-(trans)-cyclohex-4-ene-1,2-diamine dihydrochloride (102312-67-4,105249-35-2,108796-57-2,118157-55-4)

Guidance literature:

maleic acid dichloroanhydride; buta-1,3-diene; In diethyl ether; at -50 - 20 ℃; for 3h;

With trimethylsilylazide; In 1,4-dioxane; at 80 - 105 ℃;

With hydrogenchloride; In 1,4-dioxane; water; acetone;

Reference yield:

cis-4-Cyclohexen-1,2-diyl-diisocyanat (57266-64-5) → cis-cyclohex-3-enyl-1,2-diamine dihydrochloride (102312-67-4,105249-35-2,108796-57-2,118157-55-4)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; acetone; at 20 ℃; for 14h;

DOI:10.1021/jo026118a

upstream raw materials:

trans-4-cyclohexene-1,2-dicarbonyl dichloride

(1S*,2S*)-cyclohex-4-ene-1,2-dicarbohydrazide

maleic acid dichloroanhydride

buta-1,3-diene

Downstream raw materials:

bis(phenylmethyl) (1α,2β-cyclohexanediyl)bis(carbamate)

cis-cyclohex-3-enyl-1,2-diamine

cis-N,N'-bis-(prop-2-ynyl)-N,N'-bis-(p-toluenesulfonyl)-1,2-diaminocyclohex-4-ene

cis-N,N'-bis-allyl-N,N'-bis-(p-toluenesulfonyl)-1,2-diaminocyclohex-4-ene