(5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

Base Information

Chemical Name:(5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester
CAS No.:127924-58-7
Molecular Formula:C₃₄H₅₀N₂O₈Si
Molecular Weight:642.865
Hs Code.:

(5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

Synonyms:

Suppliers and Price of (5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

There total 9 articles about (5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 127924-58-7,127995-77-1
(5R,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

: 127924-58-7,127995-77-1
(5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at -78 - 25 ℃;
DOI:10.1016/S0040-4039(01)80606-7

Reference yield: 71.0%

: 116-11-0
2-Methoxypropene

: 127924-56-5
C₃₁H₄₆N₂O₈Si

: 127924-58-7,127995-77-1
(5R,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

Guidance literature:: With toluene-4-sulfonic acid; In dichloromethane;
DOI:10.1016/S0040-4039(01)80606-7

Reference yield:

: 617-55-0
dimethyl (S)-malate

: 127924-58-7,127995-77-1
(5S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3,4]oxadiazinane-3,4,5-tricarboxylic acid 3,4-di-tert-butyl ester 5-methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 88 percent / BH₃ / NaBH₄

2: 71 percent / imidazole / dimethylformamide / 48 h / Ambient temperature

3: 1.) LDA / 1.) THF

4: 71 percent / p-TSA / CH₂Cl₂

5: 75 percent / t-BuOK / tetrahydrofuran / -78 - 25 °C

With 1H-imidazole; borane; potassium tert-butylate; toluene-4-sulfonic acid; lithium diisopropyl amide; sodium tetrahydroborate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)80606-7