2-Amino-alpha-ethyl-alpha-methylbenzenemethanol

Base Information

• Chemical Name: 2-Amino-alpha-ethyl-alpha-methylbenzenemethanol
• CAS No.: 57772-51-7
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.235
• DSSTox Substance ID: DTXSID401280879
• Mol file: 57772-51-7.mol

Synonyms:SCHEMBL18759138;DTXSID401280879;57772-51-7;2-Amino-alpha-ethyl-alpha-methylbenzenemethanol

Chemical Property of 2-Amino-alpha-ethyl-alpha-methylbenzenemethanol

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 165.115364102
• Heavy Atom Count: 12
• Complexity: 149

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC(C)(C1=CC=CC=C1N)O

Technology Process of 2-Amino-alpha-ethyl-alpha-methylbenzenemethanol

There total 2 articles about 2-Amino-alpha-ethyl-alpha-methylbenzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethylmagnesium iodide (10467-10-4) + 2-aminoacetophenone (551-93-9) → 2-Amino-α-ethyl-α-methyl-benzylalkohol (57772-51-7)

Guidance literature:

In diethyl ether;

DOI:10.1002/jhet.5570360319

Reference yield:

→ 2-Amino-α-ethyl-α-methyl-benzylalkohol (57772-51-7)

Guidance literature:

Methylmagnesiumiodid, 1) o-Amino-propiophenon, Ae., sd., 1h, 2) Hydrolyse;

Reference yield:

2-Amino-α-ethyl-α-methyl-benzylalkohol (57772-51-7) → 2-(2-aminophenyl)but-2-ene (133901-59-4) + 2-(but-1-en-2-yl)aniline (246019-65-8)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 0.75h; Title compound not separated from byproducts; Heating;

DOI:10.1002/jhet.5570360319

upstream raw materials:

ethylmagnesium iodide

2-aminoacetophenone

Downstream raw materials:

(E)-N-<2-(1-methylprop-1-enyl)phenyl>phthalimide

2-(2-aminophenyl)but-2-ene

2-(but-1-en-2-yl)aniline