methyl 6-nitroindole-3-glyoxylate

Base Information

Chemical Name:methyl 6-nitroindole-3-glyoxylate
CAS No.:133053-91-5
Molecular Formula:C₁₁H₈N₂O₅
Molecular Weight:248.195
Hs Code.:

Synonyms:

Suppliers and Price of methyl 6-nitroindole-3-glyoxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
(6-Nitro-1H-indol-3-yl)oxoacetic acid methyl ester 95+%
1 g
$ 250.00

SynChem
(6-Nitro-1H-indol-3-yl)oxoacetic acid methyl ester 95+%
5 g
$ 995.00

AK Scientific
Methyl2-(6-Nitro-3-indolyl)-2-oxoacetate
1g
$ 728.00

Total 2 raw suppliers

Chemical Property of methyl 6-nitroindole-3-glyoxylate

Chemical Property:

Boiling Point:471.2±25.0 °C(Predicted)
Density:1.502±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

(6-Nitro-1H-indol-3-yl)oxoacetic acid methyl ester 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 6-nitroindole-3-glyoxylate

There total 4 articles about methyl 6-nitroindole-3-glyoxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 133053-90-4
methyl 3-(4-nitro-2-dimethylaminomethyleneaminophenyl)-pyruvate

: 133053-91-5
methyl 6-nitroindole-3-glyoxylate

Guidance literature:: With acetic acid; In ethanol; for 30h; Heating;
DOI:10.1016/S0040-4020(01)87932-1

Reference yield:

: 99-55-8
2-methyl-5-nitroaniline

: 133053-91-5
methyl 6-nitroindole-3-glyoxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / phosphorus oxychloride / 2 h / heated on a steam bath

2: 1) potassium tert-butoxide, 2) acetic acid / 1) DMF, 45 min, on a steam bath, 2) H₂O, 10 min, reflux

With potassium tert-butylate; acetic acid; trichlorophosphate;
DOI:10.1016/S0040-4020(01)87932-1

Reference yield:

: 36192-16-2
N'-(2-methyl-5-nitrophenyl)-N,N-dimethylformamidine

: 133053-91-5
methyl 6-nitroindole-3-glyoxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / potassium tert-butoxide / dimethylformamide / 0.75 h / on a steam bath

2: 93 percent / acetic acid / ethanol / 30 h / Heating

With potassium tert-butylate; acetic acid; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)87932-1