{2-[{2-[{2-[(2-Chlorocarbonylmethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetyl chloride

Base Information

• Chemical Name: {2-[{2-[{2-[(2-Chlorocarbonylmethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetyl chloride
• CAS No.: 132533-73-4
• Molecular Formula: C₃₃H₄₁Cl₂N₃O₁₀S₃
• Molecular Weight: 806.807
• Mol file: 132533-73-4.mol

Synonyms:

Chemical Property of {2-[{2-[{2-[(2-Chlorocarbonylmethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {2-[{2-[{2-[(2-Chlorocarbonylmethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetyl chloride

There total 2 articles about {2-[{2-[{2-[(2-Chlorocarbonylmethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6,9,12-triaza-3,15-dioxa-6,9,12-tritosylheptadecane-1,17-diol (83076-78-2) → {2-[{2-[{2-[(2-Chlorocarbonylmethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetyl chloride (132533-73-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / Jones'reagent / acetone / Ambient temperature

2: thionyl chloride / Heating

With thionyl chloride; Jones'reagent; In acetone;

DOI:10.1016/S0040-4039(00)97093-X

Reference yield:

{2-[{2-[{2-[(2-Carboxymethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetic acid (132533-68-7) → {2-[{2-[{2-[(2-Chlorocarbonylmethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetyl chloride (132533-73-4)

Guidance literature:

With thionyl chloride; Heating;

DOI:10.1016/S0040-4039(00)97093-X

Reference yield: 24.0%

1-(p-toluenesulfonyl)-1,4,7-triazacyclononane (129422-96-4) + {2-[{2-[{2-[(2-Chlorocarbonylmethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetyl chloride (132533-73-4) → 7,10,13,22-Tetrakis-(toluene-4-sulfonyl)-4,16-dioxa-1,7,10,13,19,22-hexaaza-bicyclo[17.5.2]hexacosane-2,18-dione (132533-69-8)

Guidance literature:

With triethylamine; In benzene;

DOI:10.1016/S0040-4039(00)97093-X

upstream raw materials:

{2-[{2-[{2-[(2-Carboxymethoxy-ethyl)-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethoxy}-acetic acid

6,9,12-triaza-3,15-dioxa-6,9,12-tritosylheptadecane-1,17-diol

Downstream raw materials:

7,10,13,22-Tetrakis-(toluene-4-sulfonyl)-4,16-dioxa-1,7,10,13,19,22-hexaaza-bicyclo[17.5.2]hexacosane-2,18-dione