Secologanin diMethyl acetal

Base Information

• Chemical Name: Secologanin diMethyl acetal
• CAS No.: 77988-07-9
• Molecular Formula: C₁₉H₃₀O₁₁
• Molecular Weight: 434.441
• Mol file: 77988-07-9.mol

Synonyms:2H-Pyran-5-carboxylicacid, 4-(2,2-dimethoxyethyl)-3-ethenyl-2-(b-D-glucopyranosyloxy)-3,4-dihydro-, methyl ester, [2S-(2a,3b,4b)]-; Secologanin acetal; Secologanin dimethyl acetal

Chemical Property of Secologanin diMethyl acetal

Chemical Property:

• Vapor Pressure: 8.93E-16mmHg at 25°C
• Boiling Point: 578.2°C at 760 mmHg
• Flash Point: 197°C
• PSA: 153.37000
• Density: 1.35g/cm³
• LogP: -1.35650

Purity/Quality:

98%Min ^*data from raw suppliers

Secologanindimethylacetal 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Secologanin Acetal is obtained from the leaves of Davidia involucrata and displays neuritogenic activity in PC12h cells.

Technology Process of Secologanin diMethyl acetal

There total 2 articles about Secologanin diMethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methanol (67-56-1) + secologanin (19351-63-4) → secologanin dimethylacetal (77988-07-9)

Guidance literature:

With acidic MSC-1 DOWEX ion exchange resin; at 20 ℃; for 4h;

DOI:10.1016/S0040-4020(97)00734-5

Reference yield:

methanol (67-56-1) + hydracyanoside D (1227940-10-4) → hydracyanoside A (1179527-28-6) + secologanin dimethylacetal (77988-07-9)

Guidance literature:

With hydrogenchloride; at 70 ℃; for 2h;

DOI:10.3987/COM-09-11886

upstream raw materials:

methanol

secologanin

hydracyanoside D

Refernces

• 1、 Wang, Zhibin,Nakamura, Seikou,Matsuda, Hisashi,Wu, Lijun,Yoshikawa, Masayuki. "New cyanoglycosides, hydracyanosides D, E, and F, from the leaves of Hydrangea macrophylla". experimental part. p. 909 - 916. Retrieved 2010/09/18.