Bisphenol A-d6 Diglycidyl Ether

Base Information

• Chemical Name: Bisphenol A-d6 Diglycidyl Ether
• CAS No.: 1346600-09-6
• Molecular Formula: C₂₁H₂₄O₄
• Molecular Weight: 346.372
• Mol file: 1346600-09-6.mol

Synonyms:

Chemical Property of Bisphenol A-d6 Diglycidyl Ether

Chemical Property:

• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Purity/Quality:

> 98% ^*data from raw suppliers

Bisphenol A-d6 Diglycidyl Ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Labelled Bisphenol A derivative. A PPARγ antagonist; exhibits estrogenic activity.

Technology Process of Bisphenol A-d6 Diglycidyl Ether

There total 2 articles about Bisphenol A-d6 Diglycidyl Ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C15H10(2)H6O2 (86588-58-1) + (S)-Glycidyl tosylate (70987-78-9,6746-81-2) → (2S,2S)-methyl-d6-2,2'-(4,4'-(propane-2,2-diyl)bis(4,1-phenylene))bis(oxy)bis(methylene)dioxirane (1346600-09-6)

Guidance literature:

C₁₅H₁₀⁽²⁾H₆O₂; With sodium hydride; In N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere;

(S)-Glycidyl tosylate; In N,N-dimethyl-formamide; at 20 ℃; for 65h; Inert atmosphere;

Reference yield: 85.0%

1,2-Epoxy-3-bromopropane (3132-64-7,82584-73-4) + d16-bisphenol A (92739-58-7,102438-62-0,86588-58-1,96210-87-6) → BADGE-d14 (110713-15-0,1346600-09-6)

Guidance literature:

d₁₆-bisphenol A; With ethanol; potassium hydroxide;

1,2-Epoxy-3-bromopropane; In acetonitrile; at 20 ℃; for 1.66667h; Reflux;

DOI:10.1021/jf904160a

Reference yield: 26.0%

(2S,2S)-methyl-d6-2,2'-(4,4'-(propane-2,2-diyl)bis(4,1-phenylene))bis(oxy)bis(methylene)dioxirane (1346600-09-6) → (2R,2S)-methyl-d6-1-fluoro-3-(4-(2-(4-(oxiran-2-yl)methoxy)phenyl)(propan-2-yl)phenoxy)propan-2-ol

Guidance literature:

With tris(dimethylamino)sulfonium trimethylsilyldifluoride; In N,N-dimethyl-formamide; at 80 ℃; for 1h;

upstream raw materials:

1,2-Epoxy-3-bromopropane

d₁₆-bisphenol A

C₁₅H₁₀⁽²⁾H₆O₂

(S)-Glycidyl tosylate