n,n-Dibutyl-2-hydroxybenzamide

Base Information

• Chemical Name: n,n-Dibutyl-2-hydroxybenzamide
• CAS No.: 68973-57-9
• Molecular Formula: C15H23 N O2
• Molecular Weight: 249.3486
• NSC Number: 91294
• DSSTox Substance ID: DTXSID00988733
• Wikidata: Q82977408
• Mol file: 68973-57-9.mol

Synonyms:n,n-dibutyl-2-hydroxybenzamide;68973-57-9;NSC91294;DTXSID00988733;NSC-91294;AKOS003613162

Chemical Property of n,n-Dibutyl-2-hydroxybenzamide

Chemical Property:

• Vapor Pressure: 9.42E-07mmHg at 25°C
• Boiling Point: 393.4°Cat760mmHg
• Flash Point: 191.7°C
• Density: 1.029g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 249.172878976
• Heavy Atom Count: 18
• Complexity: 235

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCN(CCCC)C(=O)C1=CC=CC=C1O

Technology Process of n,n-Dibutyl-2-hydroxybenzamide

There total 1 articles about n,n-Dibutyl-2-hydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

dibutylamine (111-92-2) + salicylic acid (69-72-7,25496-36-0,8052-31-1) → N,N-dibutyl-salicylamide (68973-57-9)

Guidance literature:

salicylic acid; With thionyl chloride; for 1h; Reflux;

With trimethylamine; In dichloromethane; at 0 ℃; for 4h;

dibutylamine; In dichloromethane; at 100 ℃; for 12h;

DOI:10.1002/ejic.201801096

upstream raw materials:

dibutylamine

salicylic acid

Refernces