1-BENZYL-1H-INDOL-3-YL IMIDOTHIOCARBAMATE HYDROIODIDE

Base Information

• Chemical Name: 1-BENZYL-1H-INDOL-3-YL IMIDOTHIOCARBAMATE HYDROIODIDE
• CAS No.: 1049779-48-7
• Molecular Formula: C₁₆H₁₅N₃S*HI
• Molecular Weight: 409.294
• Mol file: 1049779-48-7.mol

Synonyms:

Chemical Property of 1-BENZYL-1H-INDOL-3-YL IMIDOTHIOCARBAMATE HYDROIODIDE

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

1-Benzyl-1H-indol-3-yl imidothiocarbamate hydroiodide 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-BENZYL-1H-INDOL-3-YL IMIDOTHIOCARBAMATE HYDROIODIDE

There total 2 articles about 1-BENZYL-1H-INDOL-3-YL IMIDOTHIOCARBAMATE HYDROIODIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzylindole (3377-71-7) + thiourea (17356-08-0) → C16H15N3S*HI (1049779-48-7)

Guidance literature:

With iodine; potassium iodide; In ethanol; at 30 - 40 ℃; for 3h; Inert atmosphere;

DOI:10.1007/s11172-010-0384-9

Reference yield:

indole (120-72-9) → C16H15N3S*HI (1049779-48-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide / dimethyl sulfoxide

1.2: 3 h / 10 - 15 °C

2.1: iodine; potassium iodide / ethanol / 3 h / 30 - 40 °C / Inert atmosphere

With iodine; potassium iodide; sodium hydroxide; In ethanol; dimethyl sulfoxide;

DOI:10.1007/s11172-010-0384-9

Reference yield:

3-Bromopropionic acid (590-92-1) + C16H15N3S*HI (1049779-48-7) → [(1-benzylindol-3-yl)sulfanyl]propionic acid (1312670-75-9)

Guidance literature:

3-Bromopropionic acid; C₁₆H₁₅N₃S*HI; With hydrazine hydrate; sodium hydroxide; In ethanol; water; for 2h; Heating; Inert atmosphere;

With hydrogenchloride; In water; at 5 ℃; for 12h; pH=1;

DOI:10.1007/s11172-010-0384-9

upstream raw materials:

indole

N-benzylindole

thiourea

Downstream raw materials:

[(1-benzylindol-3-yl)sulfanyl]propionic acid

2-hydroxy-N,N-bis(2-hydroxyethyl)ethaneammonium [(1-benzylindol-3-yl)sulfanyl]acetate

[(1-benzylindol-3-yl)sulfonyl]acetic acid

2-[(1-benzylindol-3-yl)sulfonyl]propionic acid