2-Cyclopentylpyrrolidine

Base Information

Chemical Name:2-Cyclopentylpyrrolidine
CAS No.:383127-36-4
Molecular Formula:C₉H₁₇N
Molecular Weight:139.241
Hs Code.:2933998090
European Community (EC) Number:814-893-7
DSSTox Substance ID:DTXSID801313046
Mol file:383127-36-4.mol

Synonyms:2-cyclopentylpyrrolidine;383127-36-4;2-Cyclopentyl-pyrrolidine;SCHEMBL166482;DTXSID801313046;BBL020758;MFCD02663460;STK893448;AKOS000148399;VS-07115;BB 0249510;CS-0206614;EN300-51385;AB01005429-01

Suppliers and Price of 2-Cyclopentylpyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Cyclopentylpyrrolidine
250mg
$ 180.00

Crysdot
2-Cyclopentylpyrrolidine 95+%
5g
$ 677.00

Chemenu
2-Cyclopentylpyrrolidine 95%
5g
$ 640.00

Apolloscientific
2-Cyclopentylpyrrolidine 95%
1g
$ 327.00

American Custom Chemicals Corporation
2-CYCLOPENTYLPYRROLIDINE 95.00%
1G
$ 852.55

American Custom Chemicals Corporation
2-CYCLOPENTYLPYRROLIDINE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
2-CYCLOPENTYLPYRROLIDINE 95.00%
2.5G
$ 1227.82

AK Scientific
2-Cyclopentylpyrrolidine
5g
$ 1011.00

Total 7 raw suppliers

Chemical Property of 2-Cyclopentylpyrrolidine

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:139.136099547
Heavy Atom Count:10
Complexity:105

Purity/Quality:

97% ^*data from raw suppliers

2-Cyclopentylpyrrolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(C1)C2CCCN2

Technology Process of 2-Cyclopentylpyrrolidine

There total 5 articles about 2-Cyclopentylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 132959-47-8
(-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(S)-cyclopentyl-2-pyrrolidine

: 132959-38-7,383127-36-4
(-)-2(S)-Cyclopentylpyrrolidine

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol; at 25 ℃; for 19h;
DOI:10.1021/jo00007a011

Reference yield:

: 86953-79-9
tert-butyl pyrrolidine-1-carboxylate

: 1270150-32-7,383127-36-4
C₉H₁₇N

Guidance literature:: Multi-step reaction with 2 steps

1.1: N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium / diethyl ether; cyclohexane / 3.5 h / -78 °C / Inert atmosphere

1.2: 1.5 h / -78 - 20 °C / Cooling with acetone-dry ice; Inert atmosphere

1.3: 60 h / 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 1 h

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; trifluoroacetic acid; In diethyl ether; dichloromethane; cyclohexane; 1.3: |Negishi Coupling;
DOI:10.1021/ja4054114

Reference yield:

: 3400-90-6
4-oxo-4-cyclopentylbutanoic acid

: 132959-38-7,383127-36-4
(-)-2(S)-Cyclopentylpyrrolidine

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / toluene / Heating

2: 87 percent / LiAlH₄, AlCl₃ / tetrahydrofuran / a) -78 deg C, 45 min, b) -78 deg C to r.t., 20 min, c) r.t., 15 min

3: 65 percent / HCOONH₄ / 10percent Pd/C / methanol / Ambient temperature

With lithium aluminium tetrahydride; aluminium trichloride; ammonium formate; palladium on activated charcoal; In tetrahydrofuran; methanol; toluene;
DOI:10.1021/jo00032a012