C₇H₃IN₂O₂

Base Information

• Chemical Name: C₇H₃IN₂O₂
• CAS No.: 1261481-69-9
• Molecular Formula: C₇H₃IN₂O₂
• Molecular Weight: 274.018
• Hs Code.: 2926907090
• Mol file: 1261481-69-9.mol

Synonyms:

Chemical Property of C₇H₃IN₂O₂

Chemical Property:

• Boiling Point: 338.1±37.0 °C(Predicted)
• Density: 2.07±0.1 g/cm3(Predicted)

Purity/Quality:

2-Iodo-3-nitrobenzonitrile 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇H₃IN₂O₂

There total 1 articles about C₇H₃IN₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-3-nitrobenzonitrile (87331-46-2) → C7H3IN2O2 (1261481-69-9)

Guidance literature:

2-amino-3-nitrobenzonitrile; With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃; for 0.5h;

With potassium iodide; In water; at 5 - 20 ℃; for 4h;

DOI:10.1007/s12039-012-0325-2

Reference yield:

C7H3IN2O2 (1261481-69-9) → 2-iodo-3-nitrobenzamide (189125-09-5)

Guidance literature:

With dihydrogen peroxide; sodium carbonate; In acetone; at 5 - 20 ℃; for 1h;

DOI:10.1007/s12039-012-0325-2

Reference yield:

C7H3IN2O2 (1261481-69-9) → C15H10N2O3 (1431758-05-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dihydrogen peroxide; sodium carbonate / acetone / 1 h / 5 - 20 °C

2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 0.25 h / 20 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; dihydrogen peroxide; sodium carbonate; triethylamine; In acetone; 2: |Sonogashira Cross-Coupling / 2: |Sonogashira Cross-Coupling;

DOI:10.1007/s12039-012-0325-2

upstream raw materials:

2-amino-3-nitrobenzonitrile

Downstream raw materials:

2-iodo-3-nitrobenzamide

C₁₅H₁₀N₂O₃

C₁₆H₁₂N₂O₃

C₁₆H₁₂N₂O₄

Refernces