Technology Process of C19H16O
There total 4 articles about C19H16O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(naphthalen-1-ylmethylene)bis(trimethylsilane); N-(4-methoxybenzylidene)aniline;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.0833333h;
Molecular sieve;
Inert atmosphere;
With
cesium fluoride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 3h;
Overall yield = 68 %; Overall yield = 71 mg; stereoselective reaction;
Inert atmosphere;
DOI:10.1002/chem.201500475
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran / 0.08 h / -78 °C
1.2: 0.25 h / -78 °C
1.3: 0.5 h / -78 °C
2.1: n-butyllithium / tetrahydrofuran / 0.08 h / -78 °C
2.2: 0.25 h / -78 °C
2.3: 0.5 h / -78 °C
3.1: N,N-dimethyl-formamide / 0.08 h / 20 °C / Molecular sieve; Inert atmosphere
3.2: 3 h / 20 °C / Inert atmosphere
With
n-butyllithium;
In
tetrahydrofuran; N,N-dimethyl-formamide;
3.1: |Peterson Olefination / 3.2: |Peterson Olefination;
DOI:10.1002/chem.201500475
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran / 0.08 h / -78 °C
1.2: 0.25 h / -78 °C
1.3: 0.5 h / -78 °C
2.1: N,N-dimethyl-formamide / 0.08 h / 20 °C / Molecular sieve; Inert atmosphere
2.2: 3 h / 20 °C / Inert atmosphere
With
n-butyllithium;
In
tetrahydrofuran; N,N-dimethyl-formamide;
2.1: |Peterson Olefination / 2.2: |Peterson Olefination;
DOI:10.1002/chem.201500475
