Indomethacin-d4

Base Information

• Chemical Name: Indomethacin-d4
• CAS No.: 87377-08-0
• Molecular Formula: C₁₉H₁₆ClNO₄
• Molecular Weight: 361.762
• Mol file: 87377-08-0.mol

Synonyms:

Chemical Property of Indomethacin-d4

Chemical Property:

• Melting Point: 151-153°C
• Storage Temp.: Refrigerator

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

Indomethacin-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Nonsteroidal anti-inflammatory agent (NSAID)

Technology Process of Indomethacin-d4

There total 1 articles about Indomethacin-d4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

levulinic acid (123-76-2) + acetaldehyde N-(p-chlorobenzoyl)-p-methoxyphenylhydrazone*HCl-d4 (87367-52-0) → 1-(-p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid-d4 (87377-08-0)

Guidance literature:

In acetic acid; at 80 ℃; for 3h;

DOI:10.1248/cpb.31.2033

Reference yield:

1,1,1,3',3',3'-hexafluoro-propanol (920-66-1) + 1-(-p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid-d4 (87377-08-0) → C22H12(2)H4ClF6NO4

Guidance literature:

With trifluoroacetic anhydride; at 50 ℃; for 1h;

DOI:10.1248/cpb.31.2033

upstream raw materials:

levulinic acid

acetaldehyde N-(p-chlorobenzoyl)-p-methoxyphenylhydrazone*HCl-d4