1-Methyl-2,2-diphenylcyclopropanecarboxylic acid

Base Information

Chemical Name:1-Methyl-2,2-diphenylcyclopropanecarboxylic acid
CAS No.:27067-47-6
Molecular Formula:C₁₇H₁₆O₂
Molecular Weight:252.313
Hs Code.:
NSC Number:120390
DSSTox Substance ID:DTXSID80298044

Synonyms:1-Methyl-2,2-diphenylcyclopropanecarboxylic acid;27067-47-6;NSC120390;Oprea1_093124;SCHEMBL2893316;DTXSID80298044;ALTJKGMGSJVUBN-UHFFFAOYSA-N;Cyclopropanecarboxylic acid,2-diphenyl-;NSC-120390;1-methyl-2,2-diphenyl-cyclopropanecarboxylic acid

Suppliers and Price of 1-Methyl-2,2-diphenylcyclopropanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-Methyl-2,2-diphenylcyclopropanecarboxylic acid

Chemical Property:

Vapor Pressure:3.81E-07mmHg at 25°C
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:252.115029749
Heavy Atom Count:19
Complexity:332

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(CC1(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O

Technology Process of 1-Methyl-2,2-diphenylcyclopropanecarboxylic acid

There total 17 articles about 1-Methyl-2,2-diphenylcyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 6975-21-9
methyl 1-methyl-2,2-diphenylcyclopropanecarboxylate

: 35389-12-9,27067-47-6
1-methyl-2,2-diphenylcyclopropanecarboxylic acid

Guidance literature:: methyl 1-methyl-2,2-diphenylcyclopropanecarboxylate; With methanol; sodium hydroxide; water; at 70 ℃; for 16h;

With hydrogenchloride; water; In methanol;

Reference yield:

: 35389-12-9,27067-47-6
1-methyl-2,2-diphenylcyclopropanecarboxylic acid

: 4542-84-1,27067-47-6
1-methyl-2,2-diphenylcyclopropanecarboxylic acid

Guidance literature:: With brucine;
DOI:10.1021/ja01472a023

Reference yield:

: 171005-10-0
((S)-1-bromo-2,2-diphenyl-cyclopropyl)-methanol

: 27067-47-6
(S)-1-methyl-2,2-diphenylcyclopropanecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: Py

2: LiAlH₄

3: (i) nBuLi, (ii) /BRN= 1900390/

With pyridine; lithium aluminium tetrahydride;
DOI:10.1021/ja01070a017