(S)-3-phenylpropionic acid 2-octyl ester

Base Information

• Chemical Name: (S)-3-phenylpropionic acid 2-octyl ester
• CAS No.: 52126-25-7
• Molecular Formula: C₁₇H₂₆O₂
• Molecular Weight: 262.392
• Mol file: 52126-25-7.mol

Synonyms:

Chemical Property of (S)-3-phenylpropionic acid 2-octyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-3-phenylpropionic acid 2-octyl ester

There total 5 articles about (S)-3-phenylpropionic acid 2-octyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(+)-octan-2-ol (6169-06-8,113301-48-7,4128-32-9) + 3-phenyl-1-(2-thioxothiazolidin-3-yl)propan-1-one (65439-56-7) → (S)-3-phenylpropionic acid 2-octyl ester (52126-25-7)

Guidance literature:

cesium fluoride; In N,N-dimethyl-formamide; for 96h; Ambient temperature;

Reference yield: 31.0%

rac-octan-2-ol (4128-31-8,113301-48-7,4128-32-9) + vinyl ester of 3-phenylpropionic acid (54519-07-2) → (S)-3-phenylpropionic acid 2-octyl ester (52126-25-7)

Guidance literature:

With KCl-Subtilisin Bacillus lentus; In tert-butyl alcohol; at 50 ℃; for 72h;

DOI:10.1016/S0957-4166(98)00022-6

Reference yield:

3-Phenylpropionic acid (501-52-0) → (S)-3-phenylpropionic acid 2-octyl ester (52126-25-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / KOH, Pd(OAc)2 / 24 h / 20 °C

2: 31 percent / KCl-Subtilisin Bacillus lentus / 2-methyl-propan-2-ol / 72 h / 50 °C

With palladium diacetate; potassium hydroxide; KCl-Subtilisin Bacillus lentus; In tert-butyl alcohol;

DOI:10.1016/S0957-4166(98)00022-6

upstream raw materials:

(S)-2-Octanol

hydrocinnamic acid chloride

(+)-octan-2-ol

3-phenyl-1-(2-thioxothiazolidin-3-yl)propan-1-one