4-BroMo-2-ethoxybenzyl alcohol

Base Information

• Chemical Name: 4-BroMo-2-ethoxybenzyl alcohol
• CAS No.: 1094750-85-2
• Molecular Formula: C₉H₁₁BrO₂
• Molecular Weight: 231.089
• Mol file: 1094750-85-2.mol

Synonyms:

Chemical Property of 4-BroMo-2-ethoxybenzyl alcohol

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-2-ethoxybenzylalcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-BroMo-2-ethoxybenzyl alcohol

There total 6 articles about 4-BroMo-2-ethoxybenzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

ethyl bromide (74-96-4) + 5-bromo-2-(hydroxymethyl)phenol (170434-11-4) → (4-bromo-2-ethoxyphenyl)methanol (1094750-85-2)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 85 ℃; for 16h;

DOI:10.1021/acs.jmedchem.1c00957

Reference yield:

4-bromo-2-ethoxybenzoic acid (89407-43-2) → (4-bromo-2-ethoxyphenyl)methanol (1094750-85-2)

Guidance literature:

With borane-THF; In tetrahydrofuran; at 0 - 20 ℃; for 5.25h;

Reference yield:

methyl 4-bromo-2-ethoxybenzoate → (4-bromo-2-ethoxyphenyl)methanol (1094750-85-2)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol; sodium hydroxide / tetrahydrofuran / 2 h

2: borane-THF / tetrahydrofuran / 5.25 h / 0 - 20 °C

With borane-THF; ethanol; sodium hydroxide; In tetrahydrofuran;

upstream raw materials:

4-bromosalicylic acid

ethyl 4-bromo-2-ethoxybenzoate

4-bromo-2-Hydroxybenzoic Acid Methylester

4-bromo-2-ethoxybenzoic acid