3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone

Base Information

Chemical Name:3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone
CAS No.:83583-77-1
Molecular Formula:C₁₅H₁₂N₂O₃
Molecular Weight:268.272
Hs Code.:
DSSTox Substance ID:DTXSID401325627
ChEMBL ID:CHEMBL1553235

Synonyms:83583-77-1;3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone;3-hydroxy-2-(4-methoxyphenyl)quinazolin-4-one;3-hydroxy-2-(4-methoxyphenyl)-3,4-dihydroquinazolin-4-one;MLS001195321;CHEMBL1553235;DTXSID401325627;HMS2866A03;AKOS005082792;1K-503S;SMR000550614;SR-01000309003;SR-01000309003-1

Suppliers and Price of 3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:268.08479225
Heavy Atom Count:20
Complexity:402

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=O)N2O

Technology Process of 3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone

There total 6 articles about 3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: N-(2-Amino-benzoyloxy)-4-methoxy-benzamide

: 83583-77-1
3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone

Guidance literature:: In various solvent(s); Heating;

Reference yield: 47.0%

: 28005-57-4
N-(2-ethoxycarbonylphenyl)-4-methoxythiobenzamide

: 83583-77-1
3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone

Guidance literature:: With hydroxylamine hydrochloride; In pyridine; for 16h; Heating;

Reference yield:

: 16024-82-1
methyl 2-isothiocyanatobenzoate

: 83583-77-1
3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone

Guidance literature:: Multi-step reaction with 3 steps

1: anhydrous aluminum chloride / 1.) room temp., 1 h; 2.) conc. HCl, water

2: 91 percent / sodium / 0.5 h / Ambient temperature

3: 47 percent / hydroxylamine hydrochloride / pyridine / 16 h / Heating

With aluminium trichloride; hydroxylamine hydrochloride; sodium; In pyridine;