28005-57-4

Upstream product

• 64-17-5 ethanol 
• 85094-63-9 2-(4-methoxyphenyl)-4H-3,1-benzothiazin-4-one 
• 16024-82-1 methyl 2-isothiocyanatobenzoate 
• 100-66-3 methoxybenzene 

Downstream Products

• 1152-07-4 2-(4-methoxyphenyl)-3H-quinazolin-4-one 
• 83583-77-1 3-hydroxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone 
• 85094-63-9 2-(4-methoxyphenyl)-4H-3,1-benzothiazin-4-one 
• 55390-99-3 3-amino-2-(4-methoxyphenyl)-4(3H)-quinazolinone 
• 85094-68-4 N-(2-cyclohexylcarbamoylphenyl)-4-methoxythiobenzamide 
• 85094-61-7 N-cyclohexyl-N'-(2-cyclohexylcarbamoylphenyl)-4-methoxybenzamidine 
• 85094-71-9 3-(2-hydroxyethyl)-2-(4-methoxyphenyl)-4(3H)-quinazolinone 
• 85094-74-2 3-(2-acetamidoethyl)-2-(4-methoxyphenyl)-4(3H)-quinazolinone 
• 85094-72-0 3-(2-aminoethyl)-2-(4-methoxyphenyl)-4(3H)-quinazolinone 
• 85094-65-1 3-butyl-2-(4-methoxy-phenyl)-3H-quinazolin-4-one 
• 85094-70-8 2-(4-methoxyphenyl)-3-phenylamino-4(3H)-quinazolinone 
• 85094-69-5 2-(4-methoxyphenyl)-3-methylamino-4(3H)-quinazolinone 
• 85094-66-2 3-benzyl-2-(4-methoxyphenyl)-4(3H)-quinazolinone 
• 85094-62-8 6-(4-methoxyphenyl)benzimidazo<1,2-c>quinazoline 

Relevant academic research and scientific papers

Synthesis of 4(3H)-Quinazolinones from Derivatives of Methyl 2-Isothiocyanatobenzoate

Ethyl N-((2-methoxycarbonylphenyl)thiocarbamate (2), N-(2-ethoxycarbonylphenyl)-4-methoxythiobenzamide (3b), and 2-(4-methoxyphenyl)4H,-3,1-benzothiazin-4-one (4a), react with nucleophilic reagents containing at least one primary amino group to yield a variety of 2-substituted and 2,4-disubstituted 4(3H)-quinazolinones, as well as some tricyclic and tetracyclic products.