trans-1-N-benzoyl-N-<2-(methylthio)phenyl>-2-phenylethenamine

Base Information

• Chemical Name: trans-1-N-benzoyl-N-<2-(methylthio)phenyl>-2-phenylethenamine
• CAS No.: 87012-10-0
• Molecular Formula: C₂₂H₁₉NOS
• Molecular Weight: 345.465
• Mol file: 87012-10-0.mol

Synonyms:

Chemical Property of trans-1-N-benzoyl-N-<2-(methylthio)phenyl>-2-phenylethenamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-1-N-benzoyl-N-<2-(methylthio)phenyl>-2-phenylethenamine

There total 2 articles about trans-1-N-benzoyl-N-<2-(methylthio)phenyl>-2-phenylethenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzoic acid anhydride (93-97-0) → trans-1-N-benzoyl-N-<2-(methylthio)phenyl>-2-phenylethenamine (87012-10-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / toluene / 8 h / Heating

2: 1) LDA / 1) THF, -78 deg C, 45 min; 2) -78 deg C to room temp.

With lithium diisopropyl amide; In toluene;

DOI:10.1021/jo00170a042

Reference yield:

4-Benzoyl-2-phenyl-2,3-dihydro-4H-1,4-benzothiazine (87012-01-9) + methyl iodide (74-88-4) → trans-1-N-benzoyl-N-<2-(methylthio)phenyl>-2-phenylethenamine (87012-10-0) + 1-phenyl-1-<<2-(benzoylmethylamino)phenyl>thio>ethene (87012-16-6)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given; 1) THF, -78 deg C, 45 min; 2) -78 deg C to room temp.;

DOI:10.1021/jo00170a042

upstream raw materials:

4-Benzoyl-2-phenyl-2,3-dihydro-4H-1,4-benzothiazine

methyl iodide

benzoic acid anhydride