4,4'-dimethoxy-3,3',5,5'-tetrafluoroazoxybenzene

Base Information

• Chemical Name: 4,4'-dimethoxy-3,3',5,5'-tetrafluoroazoxybenzene
• CAS No.: 499-43-4
• Molecular Formula: C₁₄H₁₀F₄N₂O₃
• Molecular Weight: 330.239
• Mol file: 499-43-4.mol

Synonyms:

Chemical Property of 4,4'-dimethoxy-3,3',5,5'-tetrafluoroazoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-dimethoxy-3,3',5,5'-tetrafluoroazoxybenzene

There total 6 articles about 4,4'-dimethoxy-3,3',5,5'-tetrafluoroazoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

1,3-difluoro-2-methoxy-5-nitrobenzene (392-25-6) + methylamine hydrochloride (593-51-1) → 4,4'-dimethoxy-3,3',5,5'-tetrafluoroazoxybenzene (499-43-4) + N-methyl-2,6-difluoro-4-nitroaniline + 3-fluoro-2-methoxy-5nitrophenol + N-methyl-3-fluoro-2-methoxy-5-nitroaniline

Guidance literature:

With sodium hydroxide; In water; acetonitrile; for 1h; Ambient temperature; Irradiation;

DOI:10.1016/0040-4020(95)00343-7

Reference yield:

1,3-difluoro-2-methoxy-5-nitrobenzene (392-25-6) → 3,5-difluoro-4-methoxyaniline (363-47-3) + 4,4'-dimethoxy-3,3',5,5'-tetrafluoroazoxybenzene (499-43-4)

Guidance literature:

With methanol; platinum;

DOI:10.1021/ja01853a051

Reference yield:

1,3-difluoro-2-methoxybenzene (437-82-1) → 4,4'-dimethoxy-3,3',5,5'-tetrafluoroazoxybenzene (499-43-4)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated H₂SO₄; HNO₃

2: platinum; methanol / Hydrogenation

With methanol; sulfuric acid; nitric acid; platinum;

DOI:10.1021/ja01853a051

upstream raw materials:

1,3-difluoro-2-methoxy-5-nitrobenzene

methylamine hydrochloride

1,3-difluoro-2-methoxybenzene

3-fluoro-2-methoxyaniline

Refernces