Technology Process of 2-(2,3-dimethoxy-4-methylphenyl)-4,4-dimethyl-4,5-dihydro-oxazole
There total 1 articles about 2-(2,3-dimethoxy-4-methylphenyl)-4,4-dimethyl-4,5-dihydro-oxazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) THF, 0 deg C, 2.) THF 25 deg C, 18 h
2: nitromethane / 18 h / 70 °C
3: 20percent aq. NaOH / methanol / 44 h / Heating
With
sodium hydroxide;
In
methanol; nitromethane;
DOI:10.1039/c39880001491
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 83 percent / tetrahydrofuran / 22 h / Heating
2: 1.) 4.5 M HCl, 2.) aq. NaOH / 1.) reflux, 7 h, 2.) 100 deg C, 1 h
3: 100 percent / diethyl ether; tetrahydrofuran / 1.17 h / Heating
4: 100 percent / trifluoroacetic acid / CHCl3 / 3 h / Ambient temperature
5: 92 percent / H2 / PtO2 / ethyl acetate / 2 h / 760 Torr / Ambient temperature
6: 90 percent / 57percent HI / acetic anhydride / 5 h / Heating
With
hydrogenchloride; sodium hydroxide; hydrogen iodide; hydrogen; trifluoroacetic acid;
platinum(IV) oxide;
In
tetrahydrofuran; diethyl ether; chloroform; acetic anhydride; ethyl acetate;
