77869-39-7Relevant academic research and scientific papers
Unambiguous characterization of the sesquiterpene (7R,9E)-1,2,11- trihydroxy-1,3,5,9-bisabolatetraene through its enantioselective synthesis
Serra, Stefano,Fronza, Giovanni
supporting information; experimental part, p. 4838 - 4843 (2012/10/08)
The bisabolane sesquiterpene (7R,9E)-1,2,11-trihydroxy-1,3,5,9- bisabolatetraene previously extracted from Commiphora kua resins was prepared by enantioselective synthesis using an enzyme-mediated resolution procedure as the key step. Both the chemical st
Synthesis of the Bacterial Coenzyme Methoxatin
Gainor, James A.,Weinreb, Steven M.
, p. 2833 - 2837 (2007/10/02)
The details of a total synthesis of methoxatin (1), the coenzyme of several bacterial alcohol dehydrogenases, are presented.Methoxatin has been prepared in 13 steps by starting from 2,3-dimethoxytoluene.The successful synthetic strategy for construction of the coenzyme used a Pfitzinger synthesis for preparation of the quinoline dicarboxylic acid portion of 1 and an "umpolung" variation of the Reissert indole synthesis for annulation of the remaining pyrrole ring.
Total Synthesis of Methoxatin, the Coenzyme of Methanol Dehydrogenase and Glucose Dehydrogenase
Gainor, James A.,Weinreb, Steven M.
, p. 4317 - 4319 (2007/10/02)
The first total synthesis of the bacterial coenzyme methoxatin has been successfully completed starting from readily available 2,3-dimethoxytoluene.
Preparation and Catalytic Hydrogenation of 4,6-Dimethyl- and 4,7-Dimethyl-8-methoxycoumarins. A 4-Methyldihydrocoumarin Synthesis
Mills, Frank D.
, p. 1597 - 1600 (2007/10/02)
Reduction of the title coumarins at 1500 psi and 150 deg over 10percent palladium on charcoal provides a simple route to dihydrocoumarins and/or ethylbutanoates, hydrogenolysis products of the lactone.Lower pressures and temperatures tend to yield only th
