1-chloro-4-(2-pyridyl)butane

Base Information

Chemical Name:1-chloro-4-(2-pyridyl)butane
CAS No.:237763-52-9
Molecular Formula:C₉H₁₂ClN
Molecular Weight:169.654
Hs Code.:

Synonyms:

Suppliers and Price of 1-chloro-4-(2-pyridyl)butane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
2-(4-chlorobutyl)-Pyridine 97.00%
1G
$ 3120.00

Total 3 raw suppliers

Chemical Property of 1-chloro-4-(2-pyridyl)butane

Chemical Property:

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

2-(4-chlorobutyl)-Pyridine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-chloro-4-(2-pyridyl)butane

There total 2 articles about 1-chloro-4-(2-pyridyl)butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

: 109-06-8
α-picoline

: 109-70-6
1.3-chlorobromopropane

: 237763-52-9
1-chloro-4-(2-pyridyl)butane

Guidance literature:: α-picoline; With lithium diisopropyl amide; In tetrahydrofuran; at 20 ℃; for 3h;

1.3-chlorobromopropane; In tetrahydrofuran; at 20 ℃; for 36h;
DOI:10.1007/pl00010260

Reference yield:

: 17945-79-8
4-(alpha-Pyridyl)butanol

: 237763-52-9
1-chloro-4-(2-pyridyl)butane

Guidance literature:: With thionyl chloride; In chloroform; at 25 ℃; for 12h;
DOI:10.1021/jo051348l

Reference yield:

: 237763-52-9
1-chloro-4-(2-pyridyl)butane

: C₂₅H₂₃N₃O₉

Guidance literature:: Multi-step reaction with 4 steps

1.1: 3 h / 80 °C

1.2: 15 g / AgClO₄ / acetonitrile / 12 h / 25 °C

2.1: HClO₄ / H₂O / 28 h / 25 °C / Irradiation

2.2: 20 percent / 4-(dimethylamino)pyridine; pyridine / CH₂Cl₂ / 12 h / 25 °C

3.1: CH₃ONa / methanol / 12 h / 25 °C

4.1: 0.30 g / triethylamine / CH₂Cl₂ / 12 h / 25 °C

With perchloric acid; sodium methylate; triethylamine; In methanol; dichloromethane; water;
DOI:10.1021/jo051348l