17945-79-8

Usage

Uses

Used in Pharmaceutical Industry:
4-(Pyridin-2-yl)butan-1-ol is used as a raw material and intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of new drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
4-(Pyridin-2-yl)butan-1-ol is used as a precursor in the development of agrochemicals, such as pesticides and herbicides. Its chemical properties enable the production of effective compounds for agricultural use.
Organic Synthesis:
4-(Pyridin-2-yl)butan-1-ol is used as a key intermediate in the synthesis of complex organic molecules. Its versatility in chemical reactions makes it a valuable component in the creation of a wide range of chemical products.
While the specific hazard and toxicity characteristics of 4-(pyridin-2-yl)butan-1-ol remain largely unexplored, its applications in the pharmaceutical and agrochemical industries highlight its importance in the field of organic synthesis. Further research is needed to fully understand its potential risks and benefits.

InChI:InChI=1/C9H13NO/c11-8-4-2-6-9-5-1-3-7-10-9/h1,3,5,7,11H,2,4,6,8H2

Upstream product

• 100-69-6 2-vinylpyridine 
• 84199-92-8 diethyl 2-(2-pyridyl)ethylmalonate 
• 58530-53-3 2,4-dibromopyridine 
• 103-74-2 2-(2-Hydroxyethyl)pyridine 
• 121056-68-6 methyl 4-(pyridin-2-yl)butanoate 
• 86480-63-9 methyl(α-methoxycarbonyl)(pyridine)-2-butanoate 
• 16927-00-7 2-(2-chloroethyl)pyridine 
• 109-04-6 2-bromo-pyridine 
• 395652-44-5 4-(pyridin-2-yl)but-3-yn-1-ol 
• 84199-93-9 2-(3-ethoxycarbonylpropyl)pyridine 

Downstream Products

• 90943-32-1 4-(2-pyridinyl)butyraldehyde 
• 237763-52-9 1-chloro-4-(2-pyridyl)butane 

Relevant academic research and scientific papers

Total Synthesis of Phenanthroquinolizidine Alkaloids Using a Building Block Strategy

A concise and general strategy for the total synthesis of the phenanthroquinolizidine alkaloids has been developed. An iterative Suzuki-Miyaura coupling reaction between the requisite aryl boronic acid, 2-bromo-4,5-dimethoxyphenyl N-methyliminodiacetate (MIDA) boronate derived from boronic acid, and a suitable bromopyridine substrate bearing a homopropargyl alcohol at the 2-position generated the desired ortho-aza-terphenyl compounds. Hydrogenation of the triple bond followed by treatment with methanesulfonyl chloride afforded their corresponding tetrahydroquinolizinium ion intermediates, which were subsequently reacted with NaBH4 to provide the desired hexahydroquinolizine products. A final oxidative electrocyclization reaction gave the target phenanthroquinolizidine natural products. This synthetic approach only requires the use of three chromatographic separations throughout the entire synthesis.

FLAVOR MODULATOR HAVING PYRIDINE DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT

2-(phenylalkyloxyalkyl)pyridine derivative or a 2-(phenylalkylthioalkyl)pyridine derivative imparts, when added to food and drink or cosmetics as an active ingredient, a flavor of natural impression thereto; and in particular, when added to food and drink, the compound imparts an umami imparting or enhancing, a saltiness enhancing a sweetness enhancing, and in particular, when added to a milk or dairy product, a food or drink product containing a milk or dairy product, or a dairy replacement product, the compound provides a milk richness enhancing.

CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS

Described herein are compounds and pharmaceutical compositions which inhibit N-acylethanolamine acid amidase (NAAA). Described herein are methods for synthesizing the compounds set forth herein and methods for formulating these compounds as pharmaceutical compositions which include these compounds. Also described herein are methods of inhibiting NAAA in order to sustain the levels of palmitoylethanolamide (PEA) and other N-acylethanolamines (NAE) that are substrates for NAAA, in conditions characterized by reduced concentrations of NAE. Also, described here are methods of treating and ameliorating pain, inflammation, inflammatory diseases, and other disorders in which modulation of fatty acid ethanolamides is clinically or therapeutically relevant or in which decreased levels of NAE are associated with the disorder.

A new sequential intramolecular cyclization based on the boekelheide rearrangement

Pyrrolidines and piperidines were synthesized from (aminoalkyl)pyridine N-oxides with a general and quite efficient method developed by using di-tert-butylsilyl bis(trifluoromethanesulfonate) as a new promoter for a Boekelheide-type reaction. The use of a

Heterocyclic derivatives of 2-(3,5-dimethylphenyl)tryptamine as GnRH receptor antagonists

A series of heterocyclic 2-(3,5-dimethylphenyl)tryptamine derivatives was prepared and evaluated on a rat gonadotropin releasing hormone receptor assay. The carbon tether length and heterocyclic ring attached to the amino group of 2-(3,5-dimethylphenyl)tr

Structural Factors Affecting the Basicity of ω-Pyridylalkanols, ω-Pyridylalkanamides and ω-Pyridylalkylamines

The present paper describes the preparation by conventional methods (when not available commercially) and the pKa-determination of the α-, β- and γ-isomers of pyridylethanamide, 3-pyridylpropanamide, 4-pyridylbutanamide, 5-pyridylpentanamide, pyridylmethanol, 2-pyridylethanol, 3-pyridylpropanol, 4-pyridylbutanol, 5-pyridylpentanol, pyridylmethylamine, 2-pyridylethylamine, 3-pyridylpropylamine, 4-pyridylbutylamine, and 5-pyridylpentylamine.While a field effect accounts for many variations in pKa as a function of chain length, marked inductive effects are operative in some methyl and ethyl homologs.The pKa-decreasing influence of an intramolecular H-bond is also apparent in some lower homologs belonging to the α-series.