3-chloro-3,3-difluoropropanal diethylacetal

Base Information

• Chemical Name: 3-chloro-3,3-difluoropropanal diethylacetal
• CAS No.: 115191-42-9
• Molecular Formula: C₇H₁₃ClF₂O₂
• Molecular Weight: 202.629
• Mol file: 115191-42-9.mol

Synonyms:

Chemical Property of 3-chloro-3,3-difluoropropanal diethylacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-chloro-3,3-difluoropropanal diethylacetal

There total 1 articles about 3-chloro-3,3-difluoropropanal diethylacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + 3-bromo-1-chloro-3-ethoxy-1,1-difluoropropane (115191-41-8) → 3-chloro-3,3-difluoropropanal diethylacetal (115191-42-9)

Guidance literature:

at 0 ℃; for 1h; Yield given;

DOI:10.1016/S0022-1139(00)82015-1

Reference yield:

3-chloro-3,3-difluoropropanal diethylacetal (115191-42-9) → ethyl 3,3,3-trifluoropropanoate (352-23-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 49 percent / Caro's acid / ethanol / 1.) 5-10 deg C; 2.) room temperature, 1 day

2: 62 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0 °C

With caro's acid; tetrabutyl ammonium fluoride; In tetrahydrofuran; ethanol;

DOI:10.1016/S0022-1139(00)82015-1

upstream raw materials:

ethanol

3-bromo-1-chloro-3-ethoxy-1,1-difluoropropane

Downstream raw materials:

ethyl 3,3,3-trifluoropropanoate