Technology Process of 2-[(Benzylamino)carbonyl]-cyclopropanecarboxylicacid
There total 15 articles about 2-[(Benzylamino)carbonyl]-cyclopropanecarboxylicacid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
ethyl (±)-trans-2-(N-benzylcarbamoyl)cyclopropanecarboxylate;
With
sodium hydroxide;
In
ethanol;
at 80 ℃;
for 2h;
With
water;
DOI:10.1039/c3ob42066c
- Guidance literature:
-
Multi-step reaction with 6 steps
1: Rh2<5(S)-MEPY>4 / CH2Cl2 / Heating
2: 1.) Me3Al / 1.) hexane, 1,2-dichloroethane, RT, 30 min, 2.) hexane, 1,2-dichloroethane, reflux, 24 h
3: pyridinium chlorochromate / CH2Cl2 / 12 h / Ambient temperature
4: K2CO3 / methanol / 24 h / Ambient temperature
5: aq. CrO3 in H2SO4 / acetone / 3 h / 0 °C
6: trifluoroacetic acid / 24 h / Ambient temperature
With
Jones’ reagent; trimethylaluminum; potassium carbonate; pyridinium chlorochromate; trifluoroacetic acid;
Doyle dirhodium catalyst;
In
methanol; dichloromethane; acetone;
DOI:10.1021/jm980033d
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) Me3Al / 1.) hexane, 1,2-dichloroethane, RT, 30 min, 2.) hexane, 1,2-dichloroethane, reflux, 24 h
2: pyridinium chlorochromate / CH2Cl2 / 12 h / Ambient temperature
3: K2CO3 / methanol / 24 h / Ambient temperature
4: aq. CrO3 in H2SO4 / acetone / 3 h / 0 °C
5: trifluoroacetic acid / 24 h / Ambient temperature
With
Jones’ reagent; trimethylaluminum; potassium carbonate; pyridinium chlorochromate; trifluoroacetic acid;
In
methanol; dichloromethane; acetone;
DOI:10.1021/jm980033d
