89395-28-8

Basic information

• Product Name: 3-Oxabicyclo[3.1.0]hexan-2-one, (1R,5S)-
• Synonyms: (1R,5S)-3-oxabicyclo<3.1.0>hexan-2-one;(1R,5S)-3-oxabicylo<3.1.0>hexan-2-one;(+)-(1R,5S)-3-oxabicyclo[3.1.0]hexan-2-one;(1R,5S)-3-Oxa-bicyclo[3.1.0]hexan-2-one
• CAS NO: 89395-28-8
• Molecular Formula: C5H6O2
• Molecular Weight: 98.1014
• Mol File: 89395-28-8.mol

Chemical Properties

• CAS DataBase Reference: 3-Oxabicyclo[3.1.0]hexan-2-one, (1R,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxabicyclo[3.1.0]hexan-2-one, (1R,5S)-(89395-28-8)
• EPA Substance Registry System: 3-Oxabicyclo[3.1.0]hexan-2-one, (1R,5S)-(89395-28-8)

Safety Data

• Hazardous Substances Data: 89395-28-8(Hazardous Substances Data)

Upstream product

• 826-34-6 dimethyl cis-cyclopropane-1,2-dicarboxylate 

Downstream Products

• 910630-48-7 (1R,2S)-cis-2-(tert-butyldiphenylsilyloxymethyl)-N-methoxy-N-methyl-1-cyclopropanecarboxamide 
• 1384261-53-3 (1R,4R,6R)-3-{[5-methyl-2-(2-pyrimidinyl)phenyl]carbonyl}-4-{2-[5-(trifluoromethyl)-2-pyridinyl]ethyl}-3-azabicyclo[4.1.0]heptane 
• 1228430-63-4 1,1-dimethylethyl (1R,4S,6R)-4-(aminomethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylate 
• 151766-41-5 (1S,2S)-((E)-2-Hex-1-enyl)-cyclopropanecarbaldehyde 
• 1160474-47-4 (1R,2R)-2-Benzylcarbamoyl-cyclopropanecarboxylic acid 
• 169532-12-1 (1R,5S)-3-aza-2-oxobicyclo<3.1.0>hexane 
• 215597-45-8 (+/-)-CAMP 
• 251444-03-8 (1R,2S)-2-(tert-butyldiphenylsilyloxy)methyl-1-formylcyclopropane 
• 1027243-08-8 (1R,2S)-2-Hydroxymethyl-cyclopropanecarboxylic acid benzyl-(4-methoxy-benzyl)-amide 

Relevant articles and documents

Application of polymer-supported enzymes and reagents in the synthesis of γ-aminobutyric acid (GABA) analogues

Polymer-supported pig liver esterase was used for the resolution of meso-diesters. The enzyme can be recovered quantitatively from the reaction mixture by filtration and reused without significant loss of activity. Further transformation of the resulting enantiomerically enriched carboxylic acids through the application of polymer-supported reagents and scavengers provides a number of GABA-analogues.

Synthesis of 1-O-Acylglycerol 2,3-Cyclic Phosphate: Determination of the Absolute Structure of PHYLPA, A Specific Inhibitor of DNA Polymerase α

Four possible stereoisomers of PHYLPA, a specific inhibitor of DNA polymerase α, were synthesized in enantioselective manners.These isomers were examined for inhibition activity for DNA polymerase α, and the structure of PHYLPA was established as sodium 1-O--sn-glycerol 2,3-cyclic phosphate.