methyl 5-(3-methoxyphenyl)-3-oxopentanoate

Base Information

• Chemical Name: methyl 5-(3-methoxyphenyl)-3-oxopentanoate
• CAS No.: 109277-50-1
• Molecular Formula: C₁₃H₁₆O₄
• Molecular Weight: 236.268
• Mol file: 109277-50-1.mol

Synonyms:

Chemical Property of methyl 5-(3-methoxyphenyl)-3-oxopentanoate

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

5-(3-Methoxy-phenyl)-3-oxo-pentanoi cacid methyl ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 5-(3-methoxyphenyl)-3-oxopentanoate

There total 1 articles about methyl 5-(3-methoxyphenyl)-3-oxopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + C16H18O6 (585569-12-6) → methyl 5-(3-methoxyphenyl)-3-oxopentanoate (109277-50-1)

Guidance literature:

for 3h; Reflux;

DOI:10.1002/cmdc.201300547

Reference yield:

methyl 5-(3-methoxyphenyl)-3-oxopentanoate (109277-50-1) → methyl 3-amino-5-(3-methoxyphenyl)pent-2-enoate

Guidance literature:

With ammonium acetate; In methanol; at 35 ℃; for 16h; Inert atmosphere;

DOI:10.1002/cmdc.201300547

Reference yield:

methyl 5-(3-methoxyphenyl)-3-oxopentanoate (109277-50-1) → (E)-4-Cyclohexyl-3-(3-methoxy-benzyl)-but-3-en-2-one (109277-56-7)

Guidance literature:

Multi-step reaction with 2 steps

2: 57 percent / CH₃COOK / acetic acid / 1 h / Heating

With potassium acetate; In acetic acid;

DOI:10.1248/cpb.34.4527

upstream raw materials:

methanol

C₁₆H₁₈O₆

Downstream raw materials:

(5S,6S)-6-Cyclohexyl-5-(3-methoxy-benzyl)-dihydro-pyran-2,4-dione

(E)-4-Cyclohexyl-3-(3-methoxy-benzyl)-but-3-en-2-one

methyl 3-acetamido-5-(3-methoxyphenyl)pentanoate