2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester

Base Information

• Chemical Name: 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester
• CAS No.: 121617-85-4
• Molecular Formula: C₂₄H₁₆F₉NO₃
• Molecular Weight: 537.382
• Mol file: 121617-85-4.mol

Synonyms:

Chemical Property of 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester

There total 14 articles about 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-trifluoromethyl-2-butenoic acid ethyl ester (691-77-0) → 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester (121617-85-4,121784-48-3)

Guidance literature:

Multi-step reaction with 6 steps

1: acetonitrile / 1.) 16 h, room temperature; 2.) 24 h, 40 deg C; 3.) 4 h, 60 deg C

3: 85 percent / PPh₃ / CH₂Cl₂ / 1.) -60 deg C, 36 h; 2.) -60 deg C up to room temperature, 10 - 12 h

4: 67 percent / KOH / ethanol; H₂O / 0.5 h / Ambient temperature

5: thionyl chloride / 3 h / Heating

6: pyridine / toluene / 72 h / Ambient temperature

With pyridine; potassium hydroxide; thionyl chloride; triphenylphosphine; In ethanol; dichloromethane; water; toluene; acetonitrile;

Reference yield:

(E)-3-trifluoromethyl-2-butenoic acid ethyl ester (691-77-0) → 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester (121617-85-4,121784-48-3)

Guidance literature:

Multi-step reaction with 6 steps

1: acetonitrile / 1.) 16 h, room temperature; 2.) 24 h, 40 deg C; 3.) 4 h, 60 deg C

3: 85 percent / PPh₃ / CH₂Cl₂ / 1.) -60 deg C, 36 h; 2.) -60 deg C up to room temperature, 10 - 12 h

4: 67 percent / KOH / ethanol; H₂O / 0.5 h / Ambient temperature

5: thionyl chloride / 3 h / Heating

6: pyridine / toluene / 72 h / Ambient temperature

With pyridine; potassium hydroxide; thionyl chloride; triphenylphosphine; In ethanol; dichloromethane; water; toluene; acetonitrile;

Reference yield:

2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure (121617-83-2) → 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester (121617-85-4,121784-48-3)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / 3 h / Heating

2: pyridine / toluene / 72 h / Ambient temperature

With pyridine; thionyl chloride; In toluene;

upstream raw materials:

2-hydroxy-2-(3-phenoxyphenyl)acetonitrile

2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid

(E)-3-trifluoromethyl-2-butenoic acid ethyl ester

2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure